Literature DB >> 15588659

Effect of Rheum emodi (Revand Hindi) on renal functions in rats.

M M Azhar Alam1, Kalim Javed, M A Jafri.   

Abstract

The renal effects of water-soluble (W-S) and water-insoluble (W-INS) portions of the alcoholic extract of Revand Hindi (Rheum emodi) were investigated on cadmium chloride, mercuric chloride, potassium dichromate and gentamicin-induced nephrotoxicity in rats and normal rats by monitoring the levels of urea nitrogen and creatinine in serum. The present investigations provide evidences that W-S fraction has nephroprotective effect on all the proximal tubule segments (S1, S2 and S3) possibly through antioxidant action of the tannins present in the fraction. W-INS also improved the renal function by protecting S2 segment of proximal tubule nephrotoxicity induced by metals viz cadmium chloride and mercuric chloride in rat models, however, this fraction has been found to enhance gentamicin nephrotoxicity.

Entities:  

Mesh：

Substances：

Year:  2005        PMID： 15588659     DOI： 10.1016/j.jep.2004.08.028

Source DB:  PubMed          Journal:  J Ethnopharmacol        ISSN： 0378-8741            Impact factor:   4.360


  11 in total

1.  Protective Effect of Bauhinia purpurea on Gentamicin-induced Nephrotoxicity in Rats.

Authors:  B V S Lakshmi; N Neelima; N Kasthuri; V Umarani; M Sudhakar
Journal:  Indian J Pharm Sci       Date:  2009-09       Impact factor: 0.975

2.  Assessment of conventional and novel extraction techniques on extraction efficiency of five anthraquinones from Rheum emodi.

Authors:  Aditya U Arvindekar; Galvina R Pereira; Kirti S Laddha
Journal:  J Food Sci Technol       Date:  2015-03-21       Impact factor: 2.701

Review 3.  Ethnobotanical Uses, Phytochemistry and Pharmacology of Different Rheum Species (Polygonaceae): A Review.

Authors:  Leila Mohtashami; Mohammad Sadegh Amiri; Zahra Ayati; Mahin Ramezani; Tannaz Jamialahmadi; Seyed Ahmad Emami; Amirhossein Sahebkar
Journal:  Adv Exp Med Biol       Date:  2021       Impact factor: 2.622

4.  Reno-protective effect of Rheum turkestanicum against gentamicin-induced nephrotoxicity.

Authors:  Mohammad Taher Boroushaki; Sahar Fanoudi; Hamid Mollazadeh; Samaneh Boroumand-Noughabi; Azar Hosseini
Journal:  Iran J Basic Med Sci       Date:  2019-03       Impact factor: 2.699

5.  Medicinal plants used by the Tamang community in the Makawanpur district of central Nepal.

Authors:  Dol Raj Luitel; Maan B Rokaya; Binu Timsina; Zuzana Münzbergová
Journal:  J Ethnobiol Ethnomed       Date:  2014-01-10       Impact factor: 2.733

6.  Oral colon-specific drug delivery system reduces the nephrotoxicity of rhubarb anthraquinones when they produce purgative efficacy.

Authors:  Pei Liu; Hongwei Wei; Jinhua Chang; Guangxin Miao; Xigang Liu; Zhongsi Li; Liyan Liu; Xiangrong Zhang; Cuizhe Liu
Journal:  Exp Ther Med       Date:  2017-08-17       Impact factor: 2.447

7.  Protective Effect of Gymnema sylvestre Ethanol Extract on High Fat Diet-induced Obese Diabetic Wistar Rats.

Authors:  V Kumar; Uma Bhandari; C D Tripathi; Geetika Khanna
Journal:  Indian J Pharm Sci       Date:  2014-07       Impact factor: 0.975

8.  Development of an efficient callus proliferation system for Rheum coreanum Nakai, a rare medicinal plant growing in Democratic People's Republic of Korea.

Authors:  Song-Chol Mun; Gwan-Sim Mun
Journal:  Saudi J Biol Sci       Date:  2015-06-06       Impact factor: 4.219

9.  Protective effect of Rheum turkestanicum root against mercuric chloride-induced hepatorenal toxicity in rats.

Authors:  Azar Hosseini; Arezoo Rajabian; Sahar Fanoudi; Mahdi Farzadnia; Mohammad Taher Boroushaki
Journal:  Avicenna J Phytomed       Date:  2018 Nov-Dec

10.  Shen Shuai II Recipe Attenuates Apoptosis in 5/6 Renal Ablation/Infarction Rats by Inhibiting p53 and the Mitochondrial Pathway of Apoptosis.

Authors:  Meng Wang; Jing Yang; Chen Wang
Journal:  Oxid Med Cell Longev       Date:  2020-02-07       Impact factor: 6.543
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.