Literature DB >> 15587812

Reactivity of the hypophyseal-adrenocortical system to stress in rats with active and passive behavioral strategies.

V G Shalyapina1, V V Rakitskaya.   

Abstract

Rats with active (KHA) and passive (KLA) behavioral strategies showed no strain-related differences in basal corticosterone levels or in changes in corticosterone levels after exposure to mildly stressful stimuli. Only severe immobilization stress produced significant interstrain differences in the reactivity of the hypophyseal-adrenocortical system, as evidenced by the greater increase in blood corticosterone in KHA rats 30 min after stressing. The hormonal stress response in KHA rats was prolonged, as the elevated blood corticosterone level in these animals persisted longer than in KLA rats. The data provide evidence not only that the hypophyseal-adrenocortical systems have different sensitivities to severe stresses in these strains, but also that active and passive animals have different rates of inactivation of the stress reaction.

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Year:  2004        PMID: 15587812     DOI: 10.1023/b:neab.0000038134.82394.4c

Source DB:  PubMed          Journal:  Neurosci Behav Physiol        ISSN: 0097-0549


  15 in total

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Review 7.  [Corticoliberinergic mechanisms of the neostriatum in the neuroendocrine stress regulation].

Authors:  V G Shaliapina; E A Rybnikova; V V Rakitskaia
Journal:  Ross Fiziol Zh Im I M Sechenova       Date:  2000-11

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Review 9.  Glucocorticoids and hippocampal atrophy in neuropsychiatric disorders.

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10.  [Adaptive behavior of active and passive rats after intranasal administration of the corticotropin-releasing hormone].

Authors:  V G Shaliapina; V V Rakitskaia; E I Petrova; V I Mironova
Journal:  Ross Fiziol Zh Im I M Sechenova       Date:  2002-09
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