Literature DB >> 15585093

Molecular characterization of HIV type 1 isolates from untreated patients of Mumbai (Bombay), India, and detection of rare resistance mutations.

Alaka Deshpande1, Patricia Recordon-Pinson, Ranjana Deshmukh, Muriel Faure, Valérie Jauvin, Isabelle Garrigue, Marie-Edith Lafon, Hervé J Fleury.   

Abstract

The molecular characterization of HIV-1 isolates in drug-naive cases in the early stages of HIV disease was studied in 128 cases from Mumbai (Bombay), India. Subtype C was largely predominant followed by A-C intersubtype recombinants, one subtype A and one CRF01 AE. Compared to subtype B, subtype C exhibited an important polymorphism; the percentages of substitutions could reach more than 90%. Two isolates showed M184V substitution the reverse transcriptase indicating resistance to 3TC.

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Year:  2004        PMID： 15585093     DOI： 10.1089/aid.2004.20.1032

Source DB:  PubMed          Journal:  AIDS Res Hum Retroviruses        ISSN： 0889-2229            Impact factor:   2.205


  15 in total

1.  Suboptimal adherence associated with virological failure and resistance mutations to first-line highly active antiretroviral therapy (HAART) in Bangalore, India.

Authors:  Maria L Ekstrand; Anita Shet; Sara Chandy; Girija Singh; Ranjani Shamsundar; Vidya Madhavan; Shanmugam Saravanan; Elsa Heylen; Nagalingeswaran Kumarasamy
Journal:  Int Health       Date:  2011-03       Impact factor: 2.473

2.  Analysis of selection pressure and mutational pattern of HIV type 1 reverse transcriptase region among treated and nontreated patients.

Authors:  Uma Shanmugasundaram; Suniti Solomon; Vidya Madhavan; Murugavel G Kailapuri; Kumarasamy Nagalingeswaran; Sunil Suhas Solomon; Kenneth H Mayer; Balakrishnan Pachamuthu
Journal:  AIDS Res Hum Retroviruses       Date:  2010-09-19       Impact factor: 2.205

Review 3.  Insights into human immunodeficiency virus-hepatitis B virus co-infection in India.

Authors:  Runu Chakravarty; Ananya Pal
Journal:  World J Virol       Date:  2015-08-12

4.  HIV diversity, molecular epidemiology, and the role of recombination.

Authors:  Gustavo H Kijak; Francine E McCutchan
Journal:  Curr Infect Dis Rep       Date:  2005-11       Impact factor: 3.725

Review 5.  The challenge of HIV-1 subtype diversity.

Authors:  Barbara S Taylor; Magdalena E Sobieszczyk; Francine E McCutchan; Scott M Hammer
Journal:  N Engl J Med       Date:  2008-04-10       Impact factor: 91.245

Review 6.  Systematic review of HIV drug resistance in Southeast Asia.

Authors:  Andrew B Trotter; Steven Y Hong; Padmini Srikantiah; Iyanthi Abeyewickreme; Silvia Bertagnolio; Michael R Jordan
Journal:  AIDS Rev       Date:  2013 Jul-Sep       Impact factor: 2.500

7.  Prevalence of drug resistance in human immunodeficiency virus type 1-infected treatment-naive children in Pune, India.

Authors:  Mukesh Kumar; Sourav Sen; Rakesh K Gupta; Devidas Chaturbhuj; Srikanth P Tripathy; Ramesh S Paranjape
Journal:  AIDS Res Hum Retroviruses       Date:  2014-02-07       Impact factor: 2.205

8.  Viremia and HIV-1 drug resistance mutations among patients receiving second-line highly active antiretroviral therapy in Chennai, Southern India.

Authors:  Shanmugam Saravanan; Madhavan Vidya; Pachamuthu Balakrishnan; Rami Kantor; Sunil S Solomon; David Katzenstein; Nagalingeswaran Kumarasamy; Tokugha Yeptomi; Sathasivam Sivamalar; Samara Rifkin; Kenneth H Mayer; Suniti Solomon
Journal:  Clin Infect Dis       Date:  2012-02-09       Impact factor: 9.079

9.  Transmitted drug resistance in nonsubtype B HIV-1 infection.

Authors:  Philip A Chan; Rami Kantor
Journal:  HIV Ther       Date:  2009-09-01

Review 10.  HIV infection in India: epidemiology, molecular epidemiology and pathogenesis.

Authors:  Samir Lakhashe; Madhuri Thakar; Sheela Godbole; Srikanth Tripathy; Ramesh Paranjape
Journal:  J Biosci       Date:  2008-11       Impact factor: 1.826
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