Literature DB >> 15584722

Observation of a rectangular columnar phase in a DNA-calcium-zwitterionic lipid complex.

Jennifer J McManus1, Joachim O Rädler, Kenneth A Dawson.   

Abstract

In the presence of calcium, DNA and unilamellar liposomes of the zwitterionic lipid DPPC form a complex in which DNA strands are embedded between a lamellar phase of DPPC. In some complexes, in-plane alignment of the DNA strands occurs, where a DNA-DNA interaxial distance can be measured using small-angle X-ray scattering. Here we report a higher level of DNA organization, with a rectangular columnar phase of DNA identified within this complex structure. This observation is important in view of recent interests in creating new synthetic systems at the interface of biology.

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Year:  2004        PMID: 15584722     DOI: 10.1021/ja046105+

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN: 0002-7863            Impact factor:   15.419


  9 in total

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Journal:  Eur Biophys J       Date:  2012-06-19       Impact factor: 1.733

Review 2.  Non-viral vectors for gene-based therapy.

Authors:  Hao Yin; Rosemary L Kanasty; Ahmed A Eltoukhy; Arturo J Vegas; J Robert Dorkin; Daniel G Anderson
Journal:  Nat Rev Genet       Date:  2014-07-15       Impact factor: 53.242

3.  3D Columnar Phase of Stacked Short DNA Organized by Coherent Membrane Undulations.

Authors:  Nathan F Bouxsein; Cecília Leal; Christopher S McAllister; Youli Li; Kai K Ewert; Charles E Samuel; Cyrus R Safinya
Journal:  Langmuir       Date:  2019-08-22       Impact factor: 3.882

4.  Supramolecular polymorphism of DNA in non-cationic Lα lipid phases.

Authors:  E R Teixeira da Silva; E Andreoli de Oliveira; A Février; F Nallet; L Navailles
Journal:  Eur Phys J E Soft Matter       Date:  2011-08-29       Impact factor: 1.890

5.  The structural diversity of DNA-neutral phospholipids-divalent metal cations aggregates: a small-angle synchrotron X-ray diffraction study.

Authors:  Daniela Uhríková; Adrián Lengyel; Mária Hanulová; Sérgio S Funari; Pavol Balgavý
Journal:  Eur Biophys J       Date:  2006-07-25       Impact factor: 2.095

6.  The multiple faces of self-assembled lipidic systems.

Authors:  Guillaume Tresset
Journal:  PMC Biophys       Date:  2009-04-17

7.  Investigating Ions at Amphiphilic Monolayers with X-ray Fluorescence.

Authors:  Gerald Brezesinski; Emanuel Schneck
Journal:  Langmuir       Date:  2019-03-14       Impact factor: 3.882

Review 8.  Lipid-Nucleic Acid Complexes: Physicochemical Aspects and Prospects for Cancer Treatment.

Authors:  Ricardo Gaspar; Filipe Coelho; Bruno F B Silva
Journal:  Molecules       Date:  2020-10-28       Impact factor: 4.411

9.  A Surfactant Enables Efficient Membrane Spanning by Non-Aggregating DNA-Based Ion Channels.

Authors:  Diana Morzy; Michael Schaich; Ulrich F Keyser
Journal:  Molecules       Date:  2022-01-17       Impact factor: 4.411

  9 in total

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