Literature DB >> 15584491

Nursing home residents with multiple sclerosis: comparisons of African American residents to white residents at admission.

Robert J Buchanan1, Raymond A Martin, Miguel Zuniga, Suojin Wang, MyungSuk Kim.   

Abstract

This research profiles African American residents with multiple sclerosis (MS) at admission to the nursing facility and compares them to profiles of white residents with MS using the Minimum Data Set (MDS). We analysed MDS admission assessments for 1367 African Americans with MS and 9294 whites with MS. African American residents with MS were significantly younger at admission than white residents with MS, with almost one half of these African Americans 50 years or younger compared to only one quarter of these whites. African American residents with MS were significantly more physically disabled and cognitively impaired at admission than white residents with MS. Although there were significant racial differences in disability, there were no significant racial differences among these MS residents in the use of various therapies provided by qualified therapists. These observed racial differences among MS residents in disease manifestations, severity, progression and disability are due to multiple variables and point out the need for more research. By combining discoveries from genetics, immunology, epidemiology and virology we can gain a better understanding of the complex pathophysiology of MS and develop more effective treatments and preventive measures. Our findings also indicate potential racial disparities in the use of MS-related care, illustrating that a greater outreach effort may be needed to evaluate and treat African Americans with MS.

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Year:  2004        PMID: 15584491     DOI: 10.1191/1352458504ms1086oa

Source DB:  PubMed          Journal:  Mult Scler        ISSN: 1352-4585            Impact factor:   6.312


  5 in total

1.  An ImmunoChip study of multiple sclerosis risk in African Americans.

Authors:  Noriko Isobe; Lohith Madireddy; Pouya Khankhanian; Takuya Matsushita; Stacy J Caillier; Jayaji M Moré; Pierre-Antoine Gourraud; Jacob L McCauley; Ashley H Beecham; Laura Piccio; Joseph Herbert; Omar Khan; Jeffrey Cohen; Lael Stone; Adam Santaniello; Bruce A C Cree; Suna Onengut-Gumuscu; Stephen S Rich; Stephen L Hauser; Stephen Sawcer; Jorge R Oksenberg
Journal:  Brain       Date:  2015-03-28       Impact factor: 13.501

2.  An MRI evaluation of grey matter damage in African Americans with MS.

Authors:  Maria Petracca; Wafaa Zaaraoui; Sirio Cocozza; Roxana Vancea; Jonathan Howard; Monika M Heinig; Lazar Fleysher; Niels Oesingmann; Jean-Philippe Ranjeva; Matilde Inglese
Journal:  Mult Scler Relat Disord       Date:  2018-07-12       Impact factor: 4.339

3.  Modification of Multiple Sclerosis Phenotypes by African Ancestry at HLA.

Authors:  Bruce A C Cree; David E Reich; Omar Khan; Philip L De Jager; Ichiro Nakashima; Toshiyuki Takahashi; Amit Bar-Or; Christine Tong; Stephen L Hauser; Jorge R Oksenberg
Journal:  Arch Neurol       Date:  2009-02

4.  Multiple sclerosis susceptibility alleles in African Americans.

Authors:  B A Johnson; J Wang; E M Taylor; S J Caillier; J Herbert; O A Khan; A H Cross; P L De Jager; P-A F Gourraud; B C A Cree; S L Hauser; J R Oksenberg
Journal:  Genes Immun       Date:  2009-10-29       Impact factor: 2.676

5.  Progression, symptoms and psychosocial concerns among those severely affected by multiple sclerosis: a mixed-methods cross-sectional study of Black Caribbean and White British people.

Authors:  Jonathan Koffman; Wei Gao; Cassie Goddard; Rachel Burman; Diana Jackson; Pauline Shaw; Fiona Barnes; Eli Silber; Irene J Higginson
Journal:  PLoS One       Date:  2013-10-02       Impact factor: 3.240

  5 in total

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