| Literature DB >> 15583947 |
Geraldine Yin Taeng Ng1, Emma Harriet Baker, Katharine Florence Mary Farrer.
Abstract
Aminophylline is an adenosine receptor antagonist. Adult and paediatric studies have demonstrated a diuretic effect of aminophylline due to increased renal blood flow and the inhibition of solute reabsorption in various segments of the nephron. We report a case series of five infants with volume overload despite frusemide treatment. Aminophylline was successfully used as an adjunct diuretic with increased urine output and effective weight loss occurring in all five neonates following its introduction.Entities:
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Year: 2004 PMID: 15583947 DOI: 10.1007/s00467-004-1692-9
Source DB: PubMed Journal: Pediatr Nephrol ISSN: 0931-041X Impact factor: 3.714