Literature DB >> 15583793

Complications of major aortic and lower extremity vascular surgery.

J Nana Ghansah1, J Thomas Murphy.   

Abstract

Atheromatous disease and invasive intervention of the aortoiliac and distal arteries are common. Morbidity and mortality have been reduced through understanding and management of patient risk factors. Complications of this form of treatment affect all organ systems; mortality is most frequently caused by a cardiovascular complication (eg, myocardial infarction). Infection, leading to aortoenteric fistula is a dreaded complication, and paraplegia, though rare, is a devastating outcome. Multiorgan failure and death may result from a systemic inflammatory response syndrome. Vascular surgery for infrainguinal disease also has a significant cardiovascular complication rate. Resulting complications may affect all organs; loss of an extremity may occur. The first part of this article reviews perioperative and postoperative complications of open aortic repair and lower-extremity revascularization and addresses the issue of regional anesthesia for major vascular surgery. The second part reviews endovascular aortic repair (EVAR). EVAR is a new intervention that combines surgery and radiology. Complications of EVAR are similar to open repair, but early results suggest they may be less frequent. New technology leads to new complications; endoleaks, migration of the endoprosthesis, and surgical conversion are unique to EVAR. The benefits of EVAR may be less blood loss, shorter hospitalization, and less cardiovascular stress; the risks may be aneurysm recurrence, prolonged surveillance and repeated secondary procedures. The development of EVAR, the complications, and the anesthesia-related concerns of EVAR, including its use in management of acute abdominal aortic aneurysm are reviewed.

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Year:  2004        PMID: 15583793     DOI: 10.1177/108925320400800406

Source DB:  PubMed          Journal:  Semin Cardiothorac Vasc Anesth        ISSN: 1089-2532


  7 in total

Review 1.  Biomechanics of abdominal aortic aneurysm.

Authors:  David A Vorp
Journal:  J Biomech       Date:  2007-01-24       Impact factor: 2.712

2.  Spatiotemporal expression and localization of matrix metalloproteinas-9 in a murine model of thoracic aortic aneurysm.

Authors:  Jeffrey A Jones; John R Barbour; Abigail S Lowry; Shenikqua Bouges; Christy Beck; David M McClister; Rupak Mukherjee; John S Ikonomidis
Journal:  J Vasc Surg       Date:  2006-12       Impact factor: 4.268

Review 3.  Transforming growth factor-beta signaling in thoracic aortic aneurysm development: a paradox in pathogenesis.

Authors:  Jeffrey A Jones; Francis G Spinale; John S Ikonomidis
Journal:  J Vasc Res       Date:  2008-09-02       Impact factor: 1.934

4.  Reproducible porcine model of thoracic aortic aneurysm.

Authors:  Shaina R Eckhouse; Christina B Logdon; J Marshall Oelsen; Risha K Patel; Allison D Rice; Robert E Stroud; W Benjamin Wince; Rupak Mukherjee; Francis G Spinale; John S Ikonomidis; Jeffrey A Jones
Journal:  Circulation       Date:  2013-09-10       Impact factor: 29.690

5.  Incidence of Myocardial Infarction After High-Risk Vascular Operations in Adults.

Authors:  Yen-Yi Juo; Aditya Mantha; Ramin Ebrahimi; Boback Ziaeian; Peyman Benharash
Journal:  JAMA Surg       Date:  2017-11-15       Impact factor: 14.766

6.  Exploring the Molecular Mechanism of Thoracic Aortic Aneurysm via Bioinformatics Analysis.

Authors:  Hongfang Li; Yuzhi Zhen; Yunshuang Geng; Junyan Feng; Jun Wang; Hongsong Zhang
Journal:  Med Sci Monit       Date:  2018-03-14

7.  LncRNA LOXL1-AS is up-regulated in thoracic aortic aneurysm and regulated proliferation and apoptosis of aortic smooth muscle cells.

Authors:  Ben Huang; Shuyang Lu; Hao Lai; Jun Li; Yongxin Sun; Chunsheng Wang
Journal:  Biosci Rep       Date:  2019-09-13       Impact factor: 3.840

  7 in total

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