| Literature DB >> 15582464 |
Tania M S Silva1, Celso A Camara, Ticiano P Barbosa, André Z Soares, Luciana C da Cunha, Angelo C Pinto, Maria D Vargas.
Abstract
A series of new amino derivatives and a new partially hydrogenated derivative of the natural naphthoquinone lapachol were assayed for molluscicidal activity against Biomphalaria glabrata. These derivatives showed low to medium LC(50) values, and a 3.1 microg/mL value for the most potent derivative of the series. The toxicity is in agreement with the decrease of polar character of the tested compounds.Entities:
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Year: 2005 PMID: 15582464 DOI: 10.1016/j.bmc.2004.09.043
Source DB: PubMed Journal: Bioorg Med Chem ISSN: 0968-0896 Impact factor: 3.641