Literature DB >> 15582429

5'-Homoaristeromycin. Synthesis and antiviral activity against orthopox viruses.

Minmin Yang1, Stewart W Schneller.   

Abstract

An efficient synthesis of 5'-homoaristeromycin has been developed. This permitted an extensive antiviral analysis, which found potent activity toward vaccinia, cowpox, and monkeypox viruses. For comparative purposes, 5'-homoadenosine was made available by a newly designed route and found to be inactive.

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Year:  2005        PMID: 15582429     DOI: 10.1016/j.bmcl.2004.10.019

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN: 0960-894X            Impact factor:   2.823


  7 in total

1.  Development of a new tacaribe arenavirus infection model and its use to explore antiviral activity of a novel aristeromycin analog.

Authors:  Brian B Gowen; Min-Hui Wong; Deanna Larson; Wei Ye; Kie-Hoon Jung; Eric J Sefing; Ramona Skirpstunas; Donald F Smee; John D Morrey; Stewart W Schneller
Journal:  PLoS One       Date:  2010-09-16       Impact factor: 3.240

2.  Palladium-catalyzed decarboxylative rearrangements of allyl 2,2,2-trifluoroethyl malonates: direct access to homoallylic esters.

Authors:  Lawrence P Tardibono; Jerod Patzner; Cara Cesario; Marvin J Miller
Journal:  Org Lett       Date:  2009-09-17       Impact factor: 6.005

3.  Inhibition of Vaccinia virus entry by a broad spectrum antiviral peptide.

Authors:  S E Altmann; J C Jones; S Schultz-Cherry; C R Brandt
Journal:  Virology       Date:  2009-04-22       Impact factor: 3.616

4.  Enantioselective syntheses of carbocyclic nuleosides 5'-homocarbovir, epi-4'-homocarbovir and their cyclopropylamine analogs using facially selective Pd-mediated allylations.

Authors:  Lawrence P Tardibono; Marvin J Miller; Jan Balzarini
Journal:  Tetrahedron       Date:  2011-02-04       Impact factor: 2.457

5.  Synthesis and antiviral activity of 7-deazaneplanocin A against orthopoxviruses (vaccinia and cowpox virus).

Authors:  Balakumar Arumugham; Hyo-Joong Kim; Mark N Prichard; Earl R Kern; Chung K Chu
Journal:  Bioorg Med Chem Lett       Date:  2005-11-03       Impact factor: 2.940

6.  5'-Hydroxy-5'-homoaristeromycin: Synthesis and antiviral properties.

Authors:  Qi Chen; Chong Liu; Terry L Bowlin; Stewart W Schneller
Journal:  Bioorg Med Chem Lett       Date:  2018-03-31       Impact factor: 2.823

7.  5'-Fluoro-5'-deoxyaristeromycin.

Authors:  Weikuan Li; Xueqiang Yin; Stewart W Schneller
Journal:  Bioorg Med Chem Lett       Date:  2007-10-30       Impact factor: 2.823

  7 in total

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