S Domingo1, A Perales, V Torres, M J Alcaraz, A Pellicer. 1. Department of Obstetrics and Gynaecology, Hospital Universitario Dr. Peset, Avda. Gaspar Aguilar 90, Valencia 46017, Spain. Santiago.Domingo@ono.com
Abstract
BACKGROUND: Primary non-Hodgkin lymphoma (NHL) of the vagina is a rare location. Its association with the Epstein-Barr virus (EBV) has been only reported in another case. We present a new case, emphasizing the oncogenetic relevance of EBV. CASE REPORT: A 45-year-old woman with a pelvic pain revealed in her vaginal inspection a thick and hard vaginal plug with a "paving stone" appearance. The biopsy reported a vaginal non-Hodgkin lymphoma type B of intermediate cell, with positive result for EBV. After treatment, a complete remission was obtained. CONCLUSION: The EBV is the main responsible for the non-Hodgkin lymphoma; classified as a group I carcinogen, it has been associated with a variety of neoplastic tumors, although it is unusual with extranodal type B diffuse lymphoma.
BACKGROUND: Primary non-Hodgkin lymphoma (NHL) of the vagina is a rare location. Its association with the Epstein-Barr virus (EBV) has been only reported in another case. We present a new case, emphasizing the oncogenetic relevance of EBV. CASE REPORT: A 45-year-old woman with a pelvic pain revealed in her vaginal inspection a thick and hard vaginal plug with a "paving stone" appearance. The biopsy reported a vaginal non-Hodgkin lymphoma type B of intermediate cell, with positive result for EBV. After treatment, a complete remission was obtained. CONCLUSION: The EBV is the main responsible for the non-Hodgkin lymphoma; classified as a group I carcinogen, it has been associated with a variety of neoplastic tumors, although it is unusual with extranodal type B diffuse lymphoma.