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Literature DB >> 15580366

Microscopic polyangiitis sparing the kidneys in a long-term survivor after allogenic bone marrow transplantation and graft-versus-host disease.

Abstract

We report an unusual case of microscopic polyangiitis sparing the kidneys in a long-term survivor of allogenic bone marrow transplantation. Clinical and pathologic studies revealed cutaneous leukocytoclastic vasculitis and isolated pulmonary capillaritis. Serological studies revealed "double positive": perinuclear antineutrophil cytoplasmic (p-ANCA) antibody testing with anti-myeloperoxidase (MPO) activity and anti-glomerular basement membrane (anti-GBM) antibody. The vasculitis has been successfully controlled with prednisone and cyclophosphamide.

Entities: Chemical Disease Gene

Mesh：

Year: 2004 PMID： 15580366 DOI： 10.1007/s10067-004-1021-5

Source DB: PubMed Journal: Clin Rheumatol ISSN： 0770-3198 Impact factor: 2.980

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References

14 in total

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Journal: Nephrol Dial Transplant Date: 2002-02 Impact factor: 5.992

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Authors: S J Martin; M A Audrain; F Oksman; M Ecoiffier; M Attal; N Milpied; V L Esnault
Journal: Bone Marrow Transplant Date: 1997-07 Impact factor: 5.483

Microscopic polyangiitis sparing the kidneys in a long-term survivor after allogenic bone marrow transplantation and graft-versus-host disease.

1. ANCA +ve vasculitis after autologous PBSC transplantation.

2. ANCA +ve/anti-GBM +ve vasculitis following bone marrow transplantation.

3. Clinical practice. Long-term care after hematopoietic-cell transplantation in adults.

4. Autoantibodies in chronic GVHD: high prevalence of antinucleolar antibodies.

5. Antineutrophil cytoplasmic antibodies (ANCA) in chronic graft-versus-host disease after allogeneic bone marrow transplantation.

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