Literature DB >> 15580219

Thalidomide for severe systemic onset juvenile rheumatoid arthritis: A multicenter study.

Thomas J A Lehman1, Sharon J Schechter, Robert P Sundel, Sheila K Oliveira, Anna Huttenlocher, Karen B Onel.   

Abstract

Thirteen children with difficult systemic onset juvenile rheumatoid arthritis were treated with thalidomide. At 6 months, 11 of the 13 were able to reduce their use of prednisone ( P < .002), with a concurrent improvement in erythrocyte sedimentation rate ( P < .0001) and an increase in hemoglobin level ( P < 0.005). Juvenile rheumatoid arthritis improvement scores >/=50% were obtained by 10 of the 13 children.

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Year:  2004        PMID: 15580219     DOI: 10.1016/j.jpeds.2004.08.020

Source DB:  PubMed          Journal:  J Pediatr        ISSN: 0022-3476            Impact factor:   4.406


  16 in total

Review 1.  Update on the medical treatment of juvenile idiopathic arthritis.

Authors:  Philip J Hashkes; Ronald M Laxer
Journal:  Curr Rheumatol Rep       Date:  2006-12       Impact factor: 4.592

Review 2.  Neurological and Neuropsychiatric Adverse Effects of Dermatologic Medications.

Authors:  Melinda Liu; Yuan Yu M Huang; Sylvia Hsu; Joseph S Kass
Journal:  CNS Drugs       Date:  2016-12       Impact factor: 5.749

Review 3.  Update on the treatment of juvenile idiopathic arthritis.

Authors:  Julia G Harris; Elizabeth A Kessler; James W Verbsky
Journal:  Curr Allergy Asthma Rep       Date:  2013-08       Impact factor: 4.806

Review 4.  Systemic JIA: new developments in the understanding of the pathophysiology and therapy.

Authors:  Sebastiaan J Vastert; Wietse Kuis; Alexei A Grom
Journal:  Best Pract Res Clin Rheumatol       Date:  2009-10       Impact factor: 4.098

5.  The rise, fall and subsequent triumph of thalidomide: lessons learned in drug development.

Authors:  Waqas Rehman; Lisa M Arfons; Hillard M Lazarus
Journal:  Ther Adv Hematol       Date:  2011-10

6.  Systemic arthritis in children: a review of clinical presentation and treatment.

Authors:  R Gurion; T J A Lehman; L N Moorthy
Journal:  Int J Inflam       Date:  2011-12-25

7.  Tumor necrosis factor-alpha promotes survival in methotrexate-exposed macrophages by an NF-kappaB-dependent pathway.

Authors:  Susan Z Y Lo; James H Steer; David A Joyce
Journal:  Arthritis Res Ther       Date:  2011-02-15       Impact factor: 5.156

Review 8.  Recent developments in anti-rheumatic drugs in pediatrics: treatment of juvenile idiopathic arthritis.

Authors:  Kristen Hayward; Carol A Wallace
Journal:  Arthritis Res Ther       Date:  2009-02-23       Impact factor: 5.156

9.  Determination of thalidomide concentration in human plasma by liquid chromatography-tandem mass spectrometry.

Authors:  Nan Bai; Xiang-Yong Cui; Jin Wang; Chun-Guang Sun; He-Kun Mei; Bei-Bei Liang; Yun Cai; Xiu-Jie Song; Jing-Kai Gu; Rui Wang
Journal:  Exp Ther Med       Date:  2012-11-30       Impact factor: 2.447

Review 10.  Does thalidomide have an analgesic effect? Current status and future directions.

Authors:  Veeraindar Goli
Journal:  Curr Pain Headache Rep       Date:  2007-04
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