| Literature DB >> 15579616 |
M E Wallymahmed1, P Littler, C Clegg, M T Haqqani, I A Macfarlane.
Abstract
A 46 year old man with longstanding type 1 diabetes developed major weight loss and marked deterioration in diabetic control. He had been persistently injecting insulin into areas of abdominal lipohypertrophy within which hard collagenised fibrous tissue nodules had developed. Injecting insulin at different sites dramatically improved blood glucose control. Fibrocollagenous nodules induced by insulin injections have not been previously described. Examination of a further 73 type 1 patients revealed lipohypertrophy in 44% and hard subcutaneous nodules on two.Entities:
Mesh：
Substances：
Year: 2004 PMID： 15579616 PMCID： PMC1743164 DOI： 10.1136/pgmj.2004.019547
Source DB: PubMed Journal: Postgrad Med J ISSN： 0032-5473 Impact factor: 2.401