Literature DB >> 15578336

Radionuclide imaging metabolic activity of brown adipose tissue in a patient with pheochromocytoma.

K Fukuchi1, M Tatsumi, Y Ishida, N Oku, J Hatazawa, R L Wahl.   

Abstract

We describe a patient with extra-adrenal pheochromocytoma and high plasma norepinephrine levels. Radionuclide images of this patient obtained using (18)F-fluorodeoxyglucose and (123)I-metaiodobenzylguanidine revealed bilateral tracer accumulation in the shoulder and lower neck. The regions of radiotracer uptake corresponded to the location of human brown adipose tissue (BAT). Excessive sympathetic stimulation by high circulating catecholamine concentrations augmented the metabolic activity and tracer uptake in the BAT. This study showed that radionuclide imaging can noninvasively visualize human BAT in terms of metabolic and functional activity.

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Year:  2004        PMID: 15578336     DOI: 10.1055/s-2004-830407

Source DB:  PubMed          Journal:  Exp Clin Endocrinol Diabetes        ISSN: 0947-7349            Impact factor:   2.949


  10 in total

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  10 in total

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