OBJECTIVE: To study functional outcomes following concurrent chemoradiotherapy of head and neck cancer. METHODS: A retrospective chart review assessed diet, feeding tube use, and tracheotomy pretreatment and 3, 6, 12, and 24 months posttreatment. RESULTS: Of 196 patients who underwent chemoradiotherapy between 1990 and 2002, 148 (76%) required feeding tubes immediately posttreatment; 150 (77%) required nutritional support at 3 months. By 12 months, 92% were tube-free and 83% resumed near-normal diet. Of 17 patients (9%) with tracheotomy posttreatment, 71% were decannulated by 6 months. Stage IV disease strongly predicted prolonged feeding tube use and slow recovery of diet; age > or =60 also predicted slow recovery. Primary site, gender, and radiotherapy schedule did not predict functional recovery after adjusting for stage and age. CONCLUSION: Few patients required tracheotomy before or during chemoradiotherapy. Many patients required feeding tubes and nutritional support for several months following therapy, but most were tube-free and eating near-normal diets within 1 year. EBM RATING: C.
OBJECTIVE: To study functional outcomes following concurrent chemoradiotherapy of head and neck cancer. METHODS: A retrospective chart review assessed diet, feeding tube use, and tracheotomy pretreatment and 3, 6, 12, and 24 months posttreatment. RESULTS: Of 196 patients who underwent chemoradiotherapy between 1990 and 2002, 148 (76%) required feeding tubes immediately posttreatment; 150 (77%) required nutritional support at 3 months. By 12 months, 92% were tube-free and 83% resumed near-normal diet. Of 17 patients (9%) with tracheotomy posttreatment, 71% were decannulated by 6 months. Stage IV disease strongly predicted prolonged feeding tube use and slow recovery of diet; age > or =60 also predicted slow recovery. Primary site, gender, and radiotherapy schedule did not predict functional recovery after adjusting for stage and age. CONCLUSION: Few patients required tracheotomy before or during chemoradiotherapy. Many patients required feeding tubes and nutritional support for several months following therapy, but most were tube-free and eating near-normal diets within 1 year. EBM RATING: C.
Authors: Giorgio Capuano; Pier Carlo Gentile; Federico Bianciardi; Michela Tosti; Anna Palladino; Mario Di Palma Journal: Support Care Cancer Date: 2009-06-29 Impact factor: 3.603
Authors: Molly K Barnhart; Elizabeth C Ward; Bena Cartmill; Rachelle A Robinson; Virginia A Simms; Sophie J Chandler; Elea T Wurth; Robert I Smee Journal: Eur Arch Otorhinolaryngol Date: 2016-08-06 Impact factor: 2.503
Authors: Lisette van der Molen; Maya A van Rossum; Lori M Burkhead; Ludi E Smeele; Frans J M Hilgers Journal: Eur Arch Otorhinolaryngol Date: 2008-09-30 Impact factor: 2.503
Authors: B J Heijnen; R Speyer; B Kertscher; R Cordier; K W J Koetsenruijter; K Swan; H Bogaardt Journal: Biomed Res Int Date: 2016-09-19 Impact factor: 3.411
Authors: Lisette van der Molen; Maya A van Rossum; Annemieke H Ackerstaff; Ludi E Smeele; Coen R N Rasch; Frans J M Hilgers Journal: BMC Ear Nose Throat Disord Date: 2009-11-15