Literature DB >> 15577251

Two new lactones and one new aryl-8-oxa-bicyclo[3,2,1]oct-3-en-2-one from Descurainia sophia.

Kai Sun1, Xian Li, Wen Li, Jinhui Wang, Jianming Liu, Yi Sha.   

Abstract

Two new lactones (1, 2), descurainolide A and B, and one new aryl-8-oxa-bicyclo[3,2,1]-oct-3-en-2-one (3), descurainin, together with five known compounds (4-8), were isolated from the seeds of Descurainia sophia (L.) WEBB ex PRANTL. The structures of the new compounds were elucidated by extensive studies of their 1D, 2D NMR and HR-MS. Compounds 4 and 5 showed cytotoxicity.

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Year:  2004        PMID： 15577251     DOI： 10.1248/cpb.52.1483

Source DB:  PubMed          Journal:  Chem Pharm Bull (Tokyo)        ISSN： 0009-2363            Impact factor:   1.645


  16 in total

1.  Catalytic asymmetric synthesis of 8-oxabicyclooctanes by intermolecular [5+2] pyrylium cycloadditions.

Authors:  Michael R Witten; Eric N Jacobsen
Journal:  Angew Chem Int Ed Engl       Date:  2014-04-29       Impact factor: 15.336

2.  Optimization of supercritical fluid extraction of essential oils and fatty acids from flixweed (Descurainia Sophia L.) seed using response surface methodology and central composite design.

Authors:  Katayoun Mahdavi Ara; Mina Jowkarderis; Farhad Raofie
Journal:  J Food Sci Technol       Date:  2015-03-07       Impact factor: 2.701

3.  Dual catalysis in enantioselective oxidopyrylium-based [5 + 2] cycloadditions.

Authors:  Noah Z Burns; Michael R Witten; Eric N Jacobsen
Journal:  J Am Chem Soc       Date:  2011-08-25       Impact factor: 15.419

4.  Four new compounds from Imperata cylindrica.

Authors:  Xuan Liu; Bin-Feng Zhang; Li Yang; Gui-Xin Chou; Zheng-Tao Wang
Journal:  J Nat Med       Date:  2013-07-20       Impact factor: 2.343

5.  Cytotoxic evaluation of volatile oil from Descurainia sophia seeds on MCF-7 and HeLa cell lines.

Authors:  E Khodarahmi; G H Asghari; F Hassanzadeh; M Mirian; G A Khodarahmi
Journal:  Res Pharm Sci       Date:  2015 Mar-Apr

6.  Flixweed vs. Polyethylene Glycol in the Treatment of Childhood Functional Constipation: A Randomized Clinical Trial.

Authors:  Majid Nimrouzi; Omid Sadeghpour; Mohammad Hadi Imanieh; Mohammadreza Shams Ardekani; Alireza Salehi; Mohamad Bagher Minaei; Mohammad M Zarshenas
Journal:  Iran J Pediatr       Date:  2015-04-18       Impact factor: 0.364

7.  Searching for synergistic bronchodilators and novel therapeutic regimens for chronic lung diseases from a traditional Chinese medicine, Qingfei Xiaoyan Wan.

Authors:  Yuanyuan Hou; Binfeng Cheng; Mengge Zhou; Runping Fang; Min Jiang; Wenbin Hou; Gang Bai
Journal:  PLoS One       Date:  2014-11-14       Impact factor: 3.240

8.  Glucocappasalin Induces G2/M-Phase Arrest, Apoptosis, and Autophagy Pathways by Targeting CDK1 and PLK1 in Cervical Carcinoma Cells.

Authors:  Guangya Xu; Xueling Yan; Zhongjia Hu; Lulu Zheng; Ke Ding; Yamei Zhang; Yi Qing; Tao Liu; Lijia Cheng; Zheng Shi
Journal:  Front Pharmacol       Date:  2021-05-20       Impact factor: 5.810

9.  Helveticoside is a biologically active component of the seed extract of Descurainia sophia and induces reciprocal gene regulation in A549 human lung cancer cells.

Authors:  Bu-Yeo Kim; Jun Lee; No Soo Kim
Journal:  BMC Genomics       Date:  2015-09-18       Impact factor: 3.969

10.  Gene Expression Profile of the A549 Human Non-Small Cell Lung Carcinoma Cell Line following Treatment with the Seeds of Descurainia sophia, a Potential Anticancer Drug.

Authors:  Bu-Yeo Kim; Jun Lee; Sung Joon Park; Ok-Sun Bang; No Soo Kim
Journal:  Evid Based Complement Alternat Med       Date:  2013-06-27       Impact factor: 2.629
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