Literature DB >> 15576203

Genetic characterization of methicillin-resistant Staphylococcus aureus.

Keiichi Hiramatsu1, Shinya Watanabe, Fumihiko Takeuchi, Teruyo Ito, Tadashi Baba.   

Abstract

The genome structure of Staphylococcus aureus is analyzed. The genome is composed of two domains. The first domain, descendent from an ancestral bacterial species, contains house-keeping genes that showed highest homology to those of Bacillus species. The second domain contained the genes responsible for virulence and drug-resistance in human infection that seems to have been acquired from other bacterial species via lateral gene transfer. The latter domain constitutes the genetic information that makes S. aureus a notorious hospital pathogen.

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Year:  2004        PMID： 15576203     DOI： 10.1016/j.vaccine.2004.08.009

Source DB:  PubMed          Journal:  Vaccine        ISSN： 0264-410X            Impact factor:   3.641


  6 in total

1.  Painful nodule with induration and spreading erythema.

Authors:  Elizabeth Race; Cindy Berthelot; Jennifer Clay Cather
Journal:  Proc (Bayl Univ Med Cent)       Date:  2005-10

2.  MRSA SCCmec epidemiology in Israel: development and implementation of an MRSA SCCmec typing strategy.

Authors:  D Alon; F Abd-Elkadir; M Chowers; Y Paitan
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2011-04-10       Impact factor: 3.267

3.  Whole genome sequence of Staphylococcus saprophyticus reveals the pathogenesis of uncomplicated urinary tract infection.

Authors:  Makoto Kuroda; Atsushi Yamashita; Hideki Hirakawa; Miyuki Kumano; Kazuya Morikawa; Masato Higashide; Atsushi Maruyama; Yumiko Inose; Kimio Matoba; Hidehiro Toh; Satoru Kuhara; Masahira Hattori; Toshiko Ohta
Journal:  Proc Natl Acad Sci U S A       Date:  2005-08-31       Impact factor: 11.205

4.  Structural comparison of ten serotypes of staphylocoagulases in Staphylococcus aureus.

Authors:  S Watanabe; T Ito; F Takeuchi; M Endo; E Okuno; K Hiramatsu
Journal:  J Bacteriol       Date:  2005-06       Impact factor: 3.490

5.  Lateral transfer of genes and gene fragments in Staphylococcus extends beyond mobile elements.

Authors:  Cheong Xin Chan; Robert G Beiko; Mark A Ragan
Journal:  J Bacteriol       Date:  2011-05-27       Impact factor: 3.490

6.  Engineering of the LukS-PV and LukF-PV subunits of Staphylococcus aureus Panton-Valentine leukocidin for diagnostic and therapeutic applications.

Authors:  Charles Emeka Okolie; Alan Cockayne; Christopher Penfold; Richard James
Journal:  BMC Biotechnol       Date:  2013-11-19       Impact factor: 2.563
  6 in total

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