Literature DB >> 15576196

Transcriptome analysis of quorum-sensing regulation and virulence factor expression in Pseudomonas aeruginosa.

Victoria E Wagner1, Richard J Gillis, Barbara H Iglewski.   

Abstract

The opportunistic pathogen Pseudomonas aeruginosa possesses two well-studied quorum-sensing (QS) systems (las and rhl) that are important in the production of virulence factors, antibiotic sensitivity, and biofilm development. High-density oligonucleotide microarrays were used to further characterize the las QS system and to investigate the effect of environment (planktonic or biofilm mode of growth, absence or presence of oxygen) and nutritional conditions on detection of transcripts encoding QS-regulated virulence factors. Transcriptome results indicate that the QS system is far more complex than previously proposed. Interestingly, we found that many QS-regulated genes encoding virulence products were expressed in all conditions investigated.

Entities:  

Mesh：

Substances：

Year:  2004        PMID： 15576196     DOI： 10.1016/j.vaccine.2004.08.011

Source DB:  PubMed          Journal:  Vaccine        ISSN： 0264-410X            Impact factor:   3.641


  28 in total

1.  Organization and PprB-dependent control of the Pseudomonas aeruginosa tad Locus, involved in Flp pilus biology.

Authors:  Christophe S Bernard; Christophe Bordi; Elise Termine; Alain Filloux; Sophie de Bentzmann
Journal:  J Bacteriol       Date:  2009-01-16       Impact factor: 3.490

Review 2.  Bacterial quorum sensing: its role in virulence and possibilities for its control.

Authors:  Steven T Rutherford; Bonnie L Bassler
Journal:  Cold Spring Harb Perspect Med       Date:  2012-11-01       Impact factor: 6.915

3.  Survival and growth in the presence of elevated copper: transcriptional profiling of copper-stressed Pseudomonas aeruginosa.

Authors:  Gail M Teitzel; Ashley Geddie; Susan K De Long; Mary Jo Kirisits; Marvin Whiteley; Matthew R Parsek
Journal:  J Bacteriol       Date:  2006-10       Impact factor: 3.490

4.  The Pseudomonas aeruginosa flagellum confers resistance to pulmonary surfactant protein-A by impacting the production of exoproteases through quorum-sensing.

Authors:  Zhizhou Kuang; Yonghua Hao; Sunghei Hwang; Shiping Zhang; Eunice Kim; Henry T Akinbi; Michael J Schurr; Randall T Irvin; Daniel J Hassett; Gee W Lau
Journal:  Mol Microbiol       Date:  2011-01-06       Impact factor: 3.501

5.  Quorum-sensing antagonistic activities of azithromycin in Pseudomonas aeruginosa PAO1: a global approach.

Authors:  Yusuf Nalca; Lothar Jänsch; Florian Bredenbruch; Robert Geffers; Jan Buer; Susanne Häussler
Journal:  Antimicrob Agents Chemother       Date:  2006-05       Impact factor: 5.191

6.  Synthesis and molecular modeling provide insight into a Pseudomonas aeruginosa quorum sensing conundrum.

Authors:  Joseph S Zakhari; Isao Kinoyama; Anjali K Struss; Prasanna Pullanikat; Colin A Lowery; Matthew Lardy; Kim D Janda
Journal:  J Am Chem Soc       Date:  2011-02-24       Impact factor: 15.419

7.  A structurally unrelated mimic of a Pseudomonas aeruginosa acyl-homoserine lactone quorum-sensing signal.

Authors:  Ute Müh; Brian J Hare; Breck A Duerkop; Martin Schuster; Brian L Hanzelka; Roger Heim; Eric R Olson; E Peter Greenberg
Journal:  Proc Natl Acad Sci U S A       Date:  2006-10-30       Impact factor: 11.205

8.  Proteolytic cleavage of a C-terminal prosequence, leading to autoprocessing at the N Terminus, activates leucine aminopeptidase from Pseudomonas aeruginosa.

Authors:  Robert Sarnovsky; Jennifer Rea; Matt Makowski; Ralf Hertle; Colleen Kelly; Antonella Antignani; Diana V Pastrana; David J Fitzgerald
Journal:  J Biol Chem       Date:  2009-02-11       Impact factor: 5.157

9.  Global analysis of quorum sensing targets in the intracellular pathogen Brucella melitensis 16 M.

Authors:  Sophie Uzureau; Julien Lemaire; Edouard Delaive; Marc Dieu; Anthoula Gaigneaux; Martine Raes; Xavier De Bolle; Jean-Jacques Letesson
Journal:  J Proteome Res       Date:  2010-06-04       Impact factor: 4.466

10.  Compensatory periplasmic nitrate reductase activity supports anaerobic growth of Pseudomonas aeruginosa PAO1 in the absence of membrane nitrate reductase.

Authors:  Nadine E Van Alst; Lani A Sherrill; Barbara H Iglewski; Constantine G Haidaris
Journal:  Can J Microbiol       Date:  2009-10       Impact factor: 2.419
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.