Literature DB >> 15575790

Expedient total syntheses of rhein and diacerhein via Fries rearrangement.

Steve Tisserand1, Rachid Baati, Marc Nicolas, Charles Mioskowski.   

Abstract

Short and practical total syntheses of rhein (1) and diacerhein (2) have been achieved via a Fries rearrangement and bis-carbonylation strategy followed by cyclization in molten salt, starting from dibromoester 7.

Entities:  

Mesh:

Substances:

Year:  2004        PMID: 15575790     DOI: 10.1021/jo049228l

Source DB:  PubMed          Journal:  J Org Chem        ISSN: 0022-3263            Impact factor:   4.354


  2 in total

1.  Regioselective derivatizations of a tribrominated atropisomeric benzamide scaffold.

Authors:  Kimberly T Barrett; Scott J Miller
Journal:  Org Lett       Date:  2015-01-12       Impact factor: 6.005

2.  Structure-based approach to the development of potent and selective inhibitors of dihydrofolate reductase from cryptosporidium.

Authors:  David B Bolstad; Erin S D Bolstad; Kathleen M Frey; Dennis L Wright; Amy C Anderson
Journal:  J Med Chem       Date:  2008-10-04       Impact factor: 7.446

  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.