[Interaction of psychoemotional state and activity of the immune system].

As shown, there are direct and reverse functional connections between nervous and immune systems. Different shifts in psychoemotional reactivity induced by chronic stress or mental depression are accompanied with immunological disturbance, and on the contrary, disorders of immune state may be source of changes in mental functions. The pineal hormone melatonin, anxiolytic and antidepressant drugs simultaneously influences on the cerebral structures and immune system. These effects may be important part of specific psychopharmacological activity of the drugs.