Literature DB >> 15572120

A new cytoskeletal connection for APC: linked to actin through IQGAP.

Jennifer S Tirnauer1.   

Abstract

Migrating cells reorganize their actin and microtubule cytoskeletons in response to external cues. In this issue of Developmental Cell, Watanabe et al. now show a molecular connection between the actin crosslinking protein IQGAP1 and the microtubule-stabilizing protein APC that impacts cells' ability to migrate into a wound.

Entities:  

Mesh：

Substances：

Year:  2004        PMID： 15572120     DOI： 10.1016/j.devcel.2004.11.012

Source DB:  PubMed          Journal:  Dev Cell        ISSN： 1534-5807            Impact factor:   12.270


  11 in total

Review 1.  IQGAP1: a regulator of intracellular spacetime relativity.

Authors:  Subramaniam Malarkannan; Aradhana Awasthi; Kamalakannan Rajasekaran; Pawan Kumar; Kristina M Schuldt; Allison Bartoszek; Niranjan Manoharan; Nicholas K Goldner; Colleen M Umhoefer; Monica S Thakar
Journal:  J Immunol       Date:  2012-03-01       Impact factor: 5.422

2.  A screen for novel phosphoinositide 3-kinase effector proteins.

Authors:  Miles J Dixon; Alexander Gray; François-Michel Boisvert; Mark Agacan; Nicholas A Morrice; Robert Gourlay; Nicholas R Leslie; C Peter Downes; Ian H Batty
Journal:  Mol Cell Proteomics       Date:  2011-01-24       Impact factor: 5.911

Review 3.  IQGAP1: insights into the function of a molecular puppeteer.

Authors:  Alex M Abel; Kristina M Schuldt; Kamalakannan Rajasekaran; David Hwang; Matthew J Riese; Sridhar Rao; Monica S Thakar; Subramaniam Malarkannan
Journal:  Mol Immunol       Date:  2015-02-28       Impact factor: 4.407

Review 4.  The actin cytoskeleton in endothelial cell phenotypes.

Authors:  Nutan Prasain; Troy Stevens
Journal:  Microvasc Res       Date:  2008-10-26       Impact factor: 3.514

5.  Mutational inactivation of Apc in the intestinal epithelia compromises cellular organisation.

Authors:  Helena Rannikmae; Samantha Peel; Simon Barry; Takao Senda; Marc de la Roche
Journal:  J Cell Sci       Date:  2021-01-27       Impact factor: 5.285

Review 6.  Genetic regressive trajectories in colorectal cancer: A new hallmark of oligo-metastatic disease?

Authors:  Alessandro Ottaiano; Mariachiara Santorsola; Michele Caraglia; Luisa Circelli; Valerio Gigantino; Gerardo Botti; Guglielmo Nasti
Journal:  Transl Oncol       Date:  2021-05-21       Impact factor: 4.243

7.  Two novel human NUMB isoforms provide a potential link between development and cancer.

Authors:  Aldona Karaczyn; Mahmud Bani-Yaghoub; Roger Tremblay; Chris Kubu; Rebecca Cowling; Tamara L Adams; Igor Prudovsky; Douglas Spicer; Robert Friesel; Calvin Vary; Joseph M Verdi
Journal:  Neural Dev       Date:  2010-12-01       Impact factor: 3.842

8.  IQGAP proteins reveal an atypical phosphoinositide (aPI) binding domain with a pseudo C2 domain fold.

Authors:  Miles J Dixon; Alexander Gray; Martijn Schenning; Mark Agacan; Wolfram Tempel; Yufeng Tong; Lyudmila Nedyalkova; Hee-Won Park; Nicholas R Leslie; Daan M F van Aalten; C Peter Downes; Ian H Batty
Journal:  J Biol Chem       Date:  2012-04-05       Impact factor: 5.157

9.  Interaction between p68 RNA helicase and Ca2+-calmodulin promotes cell migration and metastasis.

Authors:  Haizhen Wang; Xueliang Gao; Jenny J Yang; Zhi-Ren Liu
Journal:  Nat Commun       Date:  2013       Impact factor: 14.919

10.  Ras GTPase-Activating-Like Protein IQGAP1 (IQGAP1) Promotes Breast Cancer Proliferation and Invasion and Correlates with Poor Clinical Outcomes.

Authors:  Fanye Zeng; Weihua Jiang; Wei Zhao; Yuxiang Fan; Yanhua Zhu; Hongliang Zhang
Journal:  Med Sci Monit       Date:  2018-05-20
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.