Literature DB >> 15571809

Ubiquitin: structures, functions, mechanisms.

Cecile M Pickart1, Michael J Eddins.   

Abstract

Ubiquitin is the founding member of a family of structurally conserved proteins that regulate a host of processes in eukaryotic cells. Ubiquitin and its relatives carry out their functions through covalent attachment to other cellular proteins, thereby changing the stability, localization, or activity of the target protein. This article reviews the basic biochemistry of these protein conjugation reactions, focusing on ubiquitin itself and emphasizing recent insights into mechanism and specificity.

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Year:  2004        PMID： 15571809     DOI： 10.1016/j.bbamcr.2004.09.019

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN： 0006-3002


  479 in total

1.  Identification of primary and secondary UBA footprints on the surface of ubiquitin in cell-mimicking crowded solution.

Authors:  Francesca Munari; Andrea Bortot; Serena Zanzoni; Mariapina D'Onofrio; David Fushman; Michael Assfalg
Journal:  FEBS Lett       Date:  2017-03-19       Impact factor: 4.124

2.  Structural basis for autoinhibition and phosphorylation-dependent activation of c-Cbl.

Authors:  Hao Dou; Lori Buetow; Andreas Hock; Gary J Sibbet; Karen H Vousden; Danny T Huang
Journal:  Nat Struct Mol Biol       Date:  2012-01-22       Impact factor: 15.369

Review 3.  Roles for the ubiquitin-proteasome pathway in protein quality control and signaling in the retina: implications in the pathogenesis of age-related macular degeneration.

Authors:  Fu Shang; Allen Taylor
Journal:  Mol Aspects Med       Date:  2012-04-10

4.  BRIZ1 and BRIZ2 proteins form a heteromeric E3 ligase complex required for seed germination and post-germination growth in Arabidopsis thaliana.

Authors:  Mon Mandy Hsia; Judy Callis
Journal:  J Biol Chem       Date:  2010-09-01       Impact factor: 5.157

5.  Drought stress-induced Rma1H1, a RING membrane-anchor E3 ubiquitin ligase homolog, regulates aquaporin levels via ubiquitination in transgenic Arabidopsis plants.

Authors:  Hyun Kyung Lee; Seok Keun Cho; Ora Son; Zhengyi Xu; Inhwan Hwang; Woo Taek Kim
Journal:  Plant Cell       Date:  2009-02-20       Impact factor: 11.277

6.  Structural insights into the ubiquitin recognition by OPTN (optineurin) and its regulation by TBK1-mediated phosphorylation.

Authors:  Faxiang Li; Daichao Xu; Yingli Wang; Zixuan Zhou; Jianping Liu; Shichen Hu; Yukang Gong; Junying Yuan; Lifeng Pan
Journal:  Autophagy       Date:  2018-02-02       Impact factor: 16.016

7.  T-cell regulator RNF125/TRAC-1 belongs to a novel family of ubiquitin ligases with zinc fingers and a ubiquitin-binding domain.

Authors:  Ana Lucia Giannini; Yifang Gao; Marie-José Bijlmakers
Journal:  Biochem J       Date:  2008-02-15       Impact factor: 3.857

Review 8.  Ubiquitin-proteasome signaling in lung injury.

Authors:  Natalia D Magnani; Laura A Dada; Jacob I Sznajder
Journal:  Transl Res       Date:  2018-04-23       Impact factor: 7.012

9.  The Spen homolog Msx2-interacting nuclear target protein interacts with the E2 ubiquitin-conjugating enzyme UbcH8.

Authors:  Junfeng Li; Jishu Wang; Xi Yang; Junlin Li; Hongyan Qin; Xiao Dong; Yangting Zhu; Liang Liang; Yingmin Liang; Hua Han
Journal:  Mol Cell Biochem       Date:  2006-04-01       Impact factor: 3.396

10.  The U4/U6 recycling factor SART3 has histone chaperone activity and associates with USP15 to regulate H2B deubiquitination.

Authors:  Lindsey Long; Joseph P Thelen; Melonnie Furgason; Mahmood Haj-Yahya; Ashraf Brik; Dongmei Cheng; Junmin Peng; Tingting Yao
Journal:  J Biol Chem       Date:  2014-02-13       Impact factor: 5.157
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