Literature DB >> 15571226

Hypoxanthine effects on cyclic AMP levels in human lymphocytes.

R J Torres1, I DeAntonio, C Prior, J G Puig.   

Abstract

We have measured hypoxanthine effect on cAMP levels in PBL in basal conditions (no agonist), and with the addition of 2-(p-[2-carboxyethyl] phenylethylamino)-5'-N-ethylcarboxamidoadenosine (CGS-21680, a specific A2 receptor agonist). We have found that hypoxanthine, at 25 microM and 50 microM concentrations, increases cAMP levels in PBL in basal and A2 agonist stimulated conditions.

Entities:  

Mesh:

Substances:

Year:  2004        PMID: 15571226     DOI: 10.1081/NCN-200027448

Source DB:  PubMed          Journal:  Nucleosides Nucleotides Nucleic Acids        ISSN: 1525-7770            Impact factor:   1.381


  1 in total

1.  Reduced levels of dopamine and altered metabolism in brains of HPRT knock-out rats: a new rodent model of Lesch-Nyhan Disease.

Authors:  Stephen Meek; Alison J Thomson; Linda Sutherland; Matthew G F Sharp; Julie Thomson; Valerie Bishop; Simone L Meddle; Yoann Gloaguen; Stefan Weidt; Karamjit Singh-Dolt; Mia Buehr; Helen K Brown; Andrew C Gill; Tom Burdon
Journal:  Sci Rep       Date:  2016-05-17       Impact factor: 4.379

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.