Literature DB >> 1557082

Muscle energy metabolism in female DMD/BMD carriers: a 31P-MR spectroscopy study.

B Barbiroli1, R Funicello, A Ferlini, P Montagna, P Zaniol.   

Abstract

31P nuclear magnetic resonance spectroscopy (31P-MRS) was used to investigate the energy metabolism of the gastrocnemius muscle in 16 DMD/BMD female carriers. No significant difference was found with the controls in the resting muscle, while all carriers showed a decreased ability to perform work, and a higher Pi/PCr ratio for comparable relative levels of steady-state work. The rate of postexercise recovery of PCr/Pi ratio was lower in all carriers. The decreased rate of PCr/Pi recovery appears to be mainly due to a decreased rate of Pi recovery. Our findings show abnormal muscle energy metabolism in DMD/BMD female carriers.

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Year:  1992        PMID： 1557082     DOI： 10.1002/mus.880150313

Source DB:  PubMed          Journal:  Muscle Nerve        ISSN： 0148-639X            Impact factor:   3.217


  11 in total

Review 1.  Advanced MRI Techniques for Muscle Imaging.

Authors:  Vivek Kalia; Doris G Leung; Darryl B Sneag; Filippo Del Grande; John A Carrino
Journal:  Semin Musculoskelet Radiol       Date:  2017-08-03       Impact factor: 1.777

2.  In vivo assessment of human skeletal muscle mitochondria respiration in health and disease.

Authors:  B Barbiroli; S Iotti; R Lodi
Journal:  Mol Cell Biochem       Date:  1997-09       Impact factor: 3.396

Review 3.  Skeletal Muscle Quantitative Nuclear Magnetic Resonance Imaging and Spectroscopy as an Outcome Measure for Clinical Trials.

Authors:  Pierre G Carlier; Benjamin Marty; Olivier Scheidegger; Paulo Loureiro de Sousa; Pierre-Yves Baudin; Eduard Snezhko; Dmitry Vlodavets
Journal:  J Neuromuscul Dis       Date:  2016-03-03

4.  Lipoic (thioctic) acid increases brain energy availability and skeletal muscle performance as shown by in vivo 31P-MRS in a patient with mitochondrial cytopathy.

Authors:  B Barbiroli; R Medori; H J Tritschler; T Klopstock; P Seibel; H Reichmann; S Iotti; R Lodi; P Zaniol
Journal:  J Neurol       Date:  1995-07       Impact factor: 4.849

5.  Metabolic abnormalities in skeletal muscle of patients receiving zidovudine therapy observed by 31P in vivo magnetic resonance spectroscopy.

Authors:  T M Sinnwell; K Sivakumar; S Soueidan; C Jay; J A Frank; A C McLaughlin; M C Dalakas
Journal:  J Clin Invest       Date:  1995-07       Impact factor: 14.808

6.  Glucocorticoids enhance muscle endurance and ameliorate Duchenne muscular dystrophy through a defined metabolic program.

Authors:  Alexander Morrison-Nozik; Priti Anand; Han Zhu; Qiming Duan; Mohamad Sabeh; Domenick A Prosdocimo; Madeleine E Lemieux; Nikolai Nordsborg; Aaron P Russell; Calum A MacRae; Anthony N Gerber; Mukesh K Jain; Saptarsi M Haldar
Journal:  Proc Natl Acad Sci U S A       Date:  2015-11-23       Impact factor: 11.205

Review 7.  Dystrophin-dependent efficiency of metabolic pathways in mouse skeletal muscles.

Authors:  A E Chinet; P C Even; A Decrouy
Journal:  Experientia       Date:  1994-06-15

8.  Brain and muscle energy metabolism studied in vivo by 31P-magnetic resonance spectroscopy in NARP syndrome.

Authors:  R Lodi; P Montagna; S Iotti; P Zaniol; P Barboni; P Puddu; B Barbiroli
Journal:  J Neurol Neurosurg Psychiatry       Date:  1994-12       Impact factor: 10.154

9.  Defects in mitochondrial ATP synthesis in dystrophin-deficient mdx skeletal muscles may be caused by complex I insufficiency.

Authors:  Emma Rybalka; Cara A Timpani; Matthew B Cooke; Andrew D Williams; Alan Hayes
Journal:  PLoS One       Date:  2014-12-26       Impact factor: 3.240

Review 10.  Metabogenic and Nutriceutical Approaches to Address Energy Dysregulation and Skeletal Muscle Wasting in Duchenne Muscular Dystrophy.

Authors:  Emma Rybalka; Cara A Timpani; Christos G Stathis; Alan Hayes; Matthew B Cooke
Journal:  Nutrients       Date:  2015-11-26       Impact factor: 5.717
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