Literature DB >> 15569945

Single-chip mechatronic microsystem for surface imaging and force response studies.

Sadik Hafizovic1, Diego Barrettino, Tormod Volden, Jan Sedivy, Kay-Uwe Kirstein, Oliver Brand, Andreas Hierlemann.   

Abstract

We report on a stand-alone single-chip (7 x 10 mm) atomic force microscopy unit including a fully integrated array of cantilevers, each of which has an individual actuation, detection, and control unit so that standard atomic force microscopy operations can be performed by means of the chip only without any external controller. The system offers drastically reduced overall size and costs as well as increased scanning speed and can be fabricated with standard complementary metal oxide semiconductor technology with some subsequent micromachining steps to form the cantilevers. Full integration of microelectronic and micromechanical components on the same chip allows for the controlling and monitoring of all system functions. The on-chip circuitry, which includes analog signal amplification and filtering stages with offset compensation, analog-to-digital converters, a powerful digital signal processor, and an on-chip digital interface for data transmission, notably improves the overall system performance. The microsystem characterization evidenced a vertical resolution of < 1 nm and a force resolution of < 1 nN as shown in the measurement results. The monolithic system represents a paradigm of a mechatronic microsystem that allows for precise and fully controlled mechanical manipulation in the nanoworld.

Entities:  

Year:  2004        PMID: 15569945      PMCID: PMC535376          DOI: 10.1073/pnas.0405725101

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN: 0027-8424            Impact factor:   11.205


  6 in total

1.  Atomic force microscopy imaging of living cells: a preliminary study of the disruptive effect of the cantilever tip on cell morphology.

Authors:  H X You; J M Lau; S Zhang; L Yu
Journal:  Ultramicroscopy       Date:  2000-02       Impact factor: 2.689

2.  Adapting atomic force microscopy for cell biology.

Authors:  P P Lehenkari; G T Charras; A Nykänen; M A Horton
Journal:  Ultramicroscopy       Date:  2000-02       Impact factor: 2.689

3.  How strong is a covalent bond?

Authors: 
Journal:  Science       Date:  1999-03-12       Impact factor: 47.728

4.  Atomic force microscope.

Authors: 
Journal:  Phys Rev Lett       Date:  1986-03-03       Impact factor: 9.161

5.  Sequence-dependent mechanics of single DNA molecules.

Authors:  M Rief; H Clausen-Schaumann; H E Gaub
Journal:  Nat Struct Biol       Date:  1999-04

6.  Nanochemical surface analyzer in CMOS technology.

Authors:  W Frank; D Lange; S Lee; A Hierlemann; N Spencer; H Baltes
Journal:  Ultramicroscopy       Date:  2002-05       Impact factor: 2.689

  6 in total
  8 in total

1.  Self-heating in piezoresistive cantilevers.

Authors:  Joseph C Doll; Elise A Corbin; William P King; Beth L Pruitt
Journal:  Appl Phys Lett       Date:  2011-05-31       Impact factor: 3.791

2.  Review: Semiconductor Piezoresistance for Microsystems.

Authors:  A Alvin Barlian; Woo-Tae Park; Joseph R Mallon; Ali J Rastegar; Beth L Pruitt
Journal:  Proc IEEE Inst Electr Electron Eng       Date:  2009       Impact factor: 10.961

3.  Real-time, multiplexed electrochemical DNA detection using an active complementary metal-oxide-semiconductor biosensor array with integrated sensor electronics.

Authors:  Peter M Levine; Ping Gong; Rastislav Levicky; Kenneth L Shepard
Journal:  Biosens Bioelectron       Date:  2008-11-01       Impact factor: 10.618

4.  High bandwidth piezoresistive force probes with integrated thermal actuation.

Authors:  Joseph C Doll; Beth L Pruitt
Journal:  J Micromech Microeng       Date:  2012-07-26       Impact factor: 1.881

Review 5.  Implantable Microimagers.

Authors:  David C Ng; Takashi Tokuda; Sadao Shiosaka; Yasuo Tano; Jun Ohta
Journal:  Sensors (Basel)       Date:  2008-05-15       Impact factor: 3.576

6.  Stiffness analysis of 3D spheroids using microtweezers.

Authors:  Devina Jaiswal; Norah Cowley; Zichao Bian; Guoan Zheng; Kevin P Claffey; Kazunori Hoshino
Journal:  PLoS One       Date:  2017-11-22       Impact factor: 3.240

7.  Electrostatically actuated encased cantilevers.

Authors:  Benoit X E Desbiolles; Gabriela Furlan; Adam M Schwartzberg; Paul D Ashby; Dominik Ziegler
Journal:  Beilstein J Nanotechnol       Date:  2018-05-08       Impact factor: 3.649

8.  Wideband Magnetic Excitation System for Atomic Force Microscopy Cantilevers with Megahertz-Order Resonance Frequency.

Authors:  Kaito Hirata; Takumi Igarashi; Keita Suzuki; Keisuke Miyazawa; Takeshi Fukuma
Journal:  Sci Rep       Date:  2020-06-04       Impact factor: 4.379

  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.