Literature DB >> 1556924

Measurement of blood-brain barrier permeability using dynamic Gd-DTPA scanning--a comparison of methods.

H B Larsson1, P S Tofts.   

Abstract

Two recently published methods of blood-brain barrier permeability measurement using Gd-DTPA scanning are compared by authors representing each group. The physiological models are reconciled. Results from both groups agree. These show that the transfer constant (the permeability surface area product per unit volume of tissue) of the defective blood-brain barrier in multiple sclerosis is in the range 1-12.10(-4) s-1.

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Year:  1992        PMID： 1556924     DOI： 10.1002/mrm.1910240119

Source DB:  PubMed          Journal:  Magn Reson Med        ISSN： 0740-3194            Impact factor:   4.668


  16 in total

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