| Literature DB >> 15568976 |
Frank Stegmeier1, Angelika Amon.
Abstract
Completion of the cell cycle requires the temporal and spatial coordination of chromosome segregation with mitotic spindle disassembly and cytokinesis. In budding yeast, the protein phosphatase Cdc14 is a key regulator of these late mitotic events. Here, we review the functions of Cdc14 and how this phosphatase is regulated to accomplish the coupling of mitotic processes. We also discuss the function and regulation of Cdc14 in other eukaryotes, emphasizing conserved features.Entities:
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Year: 2004 PMID： 15568976 DOI： 10.1146/annurev.genet.38.072902.093051
Source DB: PubMed Journal: Annu Rev Genet ISSN： 0066-4197 Impact factor: 16.830