| Literature DB >> 15568795 |
Oliver Weigenand1, Ahmed A Hussein, Namrita Lall, Jacobus J M Meyer.
Abstract
Phytochemical studies of an ethanolic extract of Euclea natalensis root bark afforded two new compounds, octahydroeuclein (1) and 20(29)-lupene-3 beta-isoferulate (2), in addition to three known compounds, shinanolone (3), lupeol, and betulin. The chemical structures of 1 and 2 were determined by spectroscopic means. Shinanolone (3) showed inhibitory activity against Gram-positive bacterial strains and a drug-sensitive strain of Mycobacterium tuberculosis at a concentration of 0.1 mg/mL.Entities:
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Year: 2004 PMID： 15568795 DOI： 10.1021/np030465d
Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050