Literature DB >> 15566466

Comparative analysis and development of microsatellite markers on swine (Sus scrofa) chromosome 1qter.

S Mikawa1, S Shimanuki, T Morozumi, M Domukai, H Shinkai, Y Uchida, A Mikawa, M Miyake, Y Miyake, N Hayashi, H Kusumoto, H Uenishi, T Hayashi, T Awata.   

Abstract

Several quantitative trait loci (QTL) have been detected on SSC1qter (Sus scrofa chromosome 1qter), including QTL for the number of vertebrae, as reported in our previous study. To provide the tools for analysis of QTLs on SSC1qter, we constructed a comparative map of swine and human. In addition, we identified 26 swine STSs and mapped 16 of them on SSC1qter using the INRA - University of Minnesota porcine radiation hybrid (IMpRH) panel. We screened a BAC library using these swine STSs and developed 35 new polymorphic microsatellite markers from the BAC clones, of which 26 were informative in our reference family. We also mapped nine microsatellite markers we had isolated previously. Consequently a total of 44 new polymorphic microsatellite markers were located within a 60-cM region of SSC1qter, spanning from SW1092 to the telomere.

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Year:  2004        PMID: 15566466     DOI: 10.1111/j.1365-2052.2004.01187.x

Source DB:  PubMed          Journal:  Anim Genet        ISSN: 0268-9146            Impact factor:   3.169


  2 in total

1.  A new 4016-marker radiation hybrid map for porcine-human genome analysis.

Authors:  Noriyuki Hamasima; Ayumi Mikawa; Hideaki Suzuki; Kohei Suzuki; Hirohide Uenishi; Takashi Awata
Journal:  Mamm Genome       Date:  2008-01-11       Impact factor: 2.957

2.  Fine mapping of a swine quantitative trait locus for number of vertebrae and analysis of an orphan nuclear receptor, germ cell nuclear factor (NR6A1).

Authors:  Satoshi Mikawa; Takeya Morozumi; Shin-Ichi Shimanuki; Takeshi Hayashi; Hirohide Uenishi; Michiko Domukai; Naohiko Okumura; Takashi Awata
Journal:  Genome Res       Date:  2007-04-06       Impact factor: 9.043

  2 in total

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