Literature DB >> 15565555

Haemostatic alterations in colorectal cancer: perspectives for future treatment.

Jakob Lykke1, Hans Jørgen Nielsen.   

Abstract

The role of the haemostatic system in colorectal cancer (CRC) is reviewed. Correlations between the activation of the haemostatic system and overall survival have been suggested. Experimental studies indicate that the haemostatic system plays a key role in growth, invasion and dissemination of tumour cells, and in tumour related angiogenesis. Additional activation by the surgical trauma and postoperative infections are discussed. Finally, anti-cancer modalities directed against regulation of the haemostatic system in CRC are considered.

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Year:  2004        PMID： 15565555     DOI： 10.1002/jso.20158

Source DB:  PubMed          Journal:  J Surg Oncol        ISSN： 0022-4790            Impact factor:   3.454


  7 in total

Review 1.  Role of von Willebrand factor levels in the prognosis of stage IV colorectal cancer: do we have enough evidence?

Authors:  I Gil-Bazo; J-A Díaz-González; J Rodríguez; J Cortés; E Calvo; J-A Páramo; J García-Foncillas
Journal:  World J Gastroenterol       Date:  2005-10-14       Impact factor: 5.742

2.  Which comorbid conditions predict complications after surgery for colorectal cancer?

Authors:  Valery E P P Lemmens; Maryska L G Janssen-Heijnen; Saskia Houterman; Kees D G W Verheij; Hendrik Martijn; Lonneke van de Poll-Franse; Jan Willem W Coebergh
Journal:  World J Surg       Date:  2007-01       Impact factor: 3.352

3.  Mutations of p53 and K-ras correlate TF expression in human colorectal carcinomas: TF downregulation as a marker of poor prognosis.

Authors:  Benqiang Rao; Yuanhong Gao; Jun Huang; Xiaoyan Gao; Xinhui Fu; Meijin Huang; Jiayin Yao; Jingping Wang; Wanglin Li; Junxiao Zhang; Huanliang Liu; Lei Wang; Jianping Wang
Journal:  Int J Colorectal Dis       Date:  2011-03-15       Impact factor: 2.571

4.  A recombinant adenovirus vector encoding the light chain of human coagulation factor VII and IgG1 Fc fragment to targeting tissue factor for colorectal cancer immunotherapy in the mouse model.

Authors:  Benqiang Rao; Yuanhong Gao; Qixu Zhou; Pei Xiao; Shuang Xia; Jingsheng Ma; Juan Luo; Tao Xiao; Shilian Le; Meijin Huang; Jianping Wang
Journal:  J Cancer Res Clin Oncol       Date:  2013-03-15       Impact factor: 4.553

5.  Brain neoplasms and coagulation-lessons from heterogeneity.

Authors:  Esterina D'Asti; Yi Fang; Janusz Rak
Journal:  Rambam Maimonides Med J       Date:  2014-10-29

6.  In Surgical Colon Cancer Patients Extended-Duration Thromboprophylaxis (30 days) with the Highest Dose of Tinzaparin (4,500 IU s.c./q.d.) Normalizes the Postoperative VEGF Levels.

Authors:  Michail Mitsis; Panagiotis Koliou; Christina Bali; Evangelia Ntounousi; Vasileios Tatsis; Vasileios Nousias; Georgios D Lianos; Georgios Vartholomatos; Dimitrios Nastos
Journal:  J Cancer       Date:  2017-08-25       Impact factor: 4.207

7.  Clinical significance of coagulation factors in operable colorectal cancer.

Authors:  Suee Lee; Seok Jae Huh; Sung Yong Oh; Myeong Seok Koh; Sung-Hyun Kim; Ji Hyun Lee; Jin Young Han; Hong Jo Choi; Su Jin Kim; Hyo-Jin Kim
Journal:  Oncol Lett       Date:  2017-04-20       Impact factor: 2.967
  7 in total

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