Literature DB >> 15565252

Biological activities of pyridoacridines.

Kathryn M Marshall1, Louis R Barrows.   

Abstract

This review consolidates biological activity data reported for pyridoacridine 1 molecules in the literature from 1983-2003 into several tables with brief discussions of assays used and results obtained. This review summarizes recent progress in structure activity relationships for analogues of amphimedine 2 and ascididemin 3 classes of pyridoacridines and correlates reported molecular mechanisms of action with biological activities.

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Year:  2004        PMID： 15565252     DOI： 10.1039/b401662a

Source DB:  PubMed          Journal:  Nat Prod Rep        ISSN： 0265-0568            Impact factor:   13.423


  17 in total

1.  Pyrroloacridine alkaloids from Plakortis quasiamphiaster: structures and bioactivity.

Authors:  Paul Ralifo; Laura Sanchez; Nadine C Gassner; Karen Tenney; R Scott Lokey; Theodore R Holman; Frederick A Valeriote; Phillip Crews
Journal:  J Nat Prod       Date:  2007-01       Impact factor: 4.050

2.  The secret to a successful relationship: lasting chemistry between ascidians and their symbiotic bacteria.

Authors:  Eric W Schmidt
Journal:  Invertebr Biol       Date:  2015-03-01       Impact factor: 1.250

3.  Species specificity of symbiosis and secondary metabolism in ascidians.

Authors:  Ma Diarey B Tianero; Jason C Kwan; Thomas P Wyche; Angela P Presson; Michael Koch; Louis R Barrows; Tim S Bugni; Eric W Schmidt
Journal:  ISME J       Date:  2014-08-29       Impact factor: 10.302

Review 4.  Life in cellulose houses: symbiotic bacterial biosynthesis of ascidian drugs and drug leads.

Authors:  Eric W Schmidt; Mohamed S Donia
Journal:  Curr Opin Biotechnol       Date:  2010-11-01       Impact factor: 9.740

5.  Naphthyridines part 4: unprecedented synthesis of polyfunctionally substituted benzo[c][2,7]naphthyridines and benzo[c]pyrimido[4,5,6-ij][2,7]naphthyridines with structural analogy to pyrido[4,3,2-mn]acridines present in the marine tetracyclic pyridoacridine alkaloids.

Authors:  Ramadan A Mekheimer; Mariam A Al-Sheikh; Hanadi Y Medrasi; Ghayah A Bahatheg
Journal:  Mol Divers       Date:  2017-11-21       Impact factor: 2.943

6.  Deoxyamphimedine, a pyridoacridine alkaloid, damages DNA via the production of reactive oxygen species.

Authors:  Kathryn M Marshall; Cynthia D Andjelic; Deniz Tasdemir; Gisela P Concepción; Chris M Ireland; Louis R Barrows
Journal:  Mar Drugs       Date:  2009-05-25       Impact factor: 5.118

7.  The total synthesis of neoamphimedine.

Authors:  Daniel V LaBarbera; Tim S Bugni; Chris M Ireland
Journal:  J Org Chem       Date:  2007-09-27       Impact factor: 4.354

8.  Evaluation of pyridoacridine alkaloids in a zebrafish phenotypic assay.

Authors:  Xiaomei Wei; Tim S Bugni; Mary Kay Harper; Imelda T Sandoval; Elizabeth J Manos; Jennifer Swift; Ryan M Van Wagoner; David A Jones; Chris M Ireland
Journal:  Mar Drugs       Date:  2010-06-02       Impact factor: 5.118

9.  Synthesis and Evaluation of the Tetracyclic Ring-System of Isocryptolepine and Regioiso-Mers for Antimalarial, Antiproliferative and Antimicrobial Activities.

Authors:  Katja S Håheim; Emil Lindbäck; Kah Ni Tan; Marte Albrigtsen; Ida T Urdal Helgeland; Clémence Lauga; Théodora Matringe; Emily K Kennedy; Jeanette H Andersen; Vicky M Avery; Magne O Sydnes
Journal:  Molecules       Date:  2021-05-30       Impact factor: 4.411

10.  Synthesis, DNA binding and antitumor evaluation of styelsamine and cystodytin analogues.

Authors:  Hugo K H Fong; Brent R Copp
Journal:  Mar Drugs       Date:  2013-01-28       Impact factor: 5.118
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