Literature DB >> 15561882

The synthetic N-terminal peptide of human lactoferrin, hLF(1-11), is highly effective against experimental infection caused by multidrug-resistant Acinetobacter baumannii.

Lenie Dijkshoorn1, Carlo P J M Brouwer, Sylvia J P Bogaards, Alexandr Nemec, Peterhans J van den Broek, Peter H Nibbering.   

Abstract

The lactoferrin-derived peptide hLF(1-11), but not its control peptide, was highly effective against five multidrug-resistant Acinetobacter baumannii strains in vitro (3 to 4 log reduction) and against four of these strains in an experimental infection in mice (2 to 3 log reduction). Therefore, this peptide is a promising candidate as a novel agent against infections with multidrug-resistant A. baumannii.

Entities:  

Mesh：

Substances：

Year:  2004        PMID： 15561882      PMCID： PMC529198          DOI： 10.1128/AAC.48.12.4919-4921.2004

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  16 in total

Review 1.  The threat from the pink corner.

Authors:  David M Livermore
Journal:  Ann Med       Date:  2003       Impact factor: 4.709

2.  Technetium-99m labelled antimicrobial peptides discriminate between bacterial infections and sterile inflammations.

Authors:  M M Welling; A Paulusma-Annema; H S Balter; E K Pauwels; P H Nibbering
Journal:  Eur J Nucl Med       Date:  2000-03

3.  Lactoferrin stimulates A Staphylococcus aureus killing activity of bovine phagocytes in the mammary gland.

Authors:  Kenzo Kai; Ken-ichi Komine; Yumiko Komine; Toshinobu Kuroishi; Tomoyuki Kozutsumi; Jin Kobayashi; Minoru Ohta; Hajime Kitamura; Katsuo Kumagai
Journal:  Microbiol Immunol       Date:  2002       Impact factor: 1.955

4.  Enhanced Th1 response to Staphylococcus aureus infection in human lactoferrin-transgenic mice.

Authors:  Cristina Guillén; Iain B McInnes; Diane M Vaughan; Sharada Kommajosyula; Patrick H C Van Berkel; Bernard P Leung; Antonio Aguila; Jeremy H Brock
Journal:  J Immunol       Date:  2002-04-15       Impact factor: 5.422

Review 5.  The impact of carbapenemases on antimicrobial development and therapy.

Authors:  David M Livermore
Journal:  Curr Opin Investig Drugs       Date:  2002-02

6.  Human lactoferrin and peptides derived from its N terminus are highly effective against infections with antibiotic-resistant bacteria.

Authors:  P H Nibbering; E Ravensbergen; M M Welling; L A van Berkel; P H van Berkel; E K Pauwels; J H Nuijens
Journal:  Infect Immun       Date:  2001-03       Impact factor: 3.441

7.  Long-term predominance of two pan-European clones among multi-resistant Acinetobacter baumannii strains in the Czech Republic.

Authors:  Alexandr Nemec; Lenie Dijkshoorn; Tanny J K van der Reijden
Journal:  J Med Microbiol       Date:  2004-02       Impact factor: 2.472

8.  One of two human lactoferrin variants exhibits increased antibacterial and transcriptional activation activities and is associated with localized juvenile periodontitis.

Authors:  Kabilan Velliyagounder; Jeffrey B Kaplan; David Furgang; Diana Legarda; Gill Diamond; Ruth E Parkin; Daniel H Fine
Journal:  Infect Immun       Date:  2003-11       Impact factor: 3.441

9.  Citywide clonal outbreak of multiresistant Acinetobacter baumannii and Pseudomonas aeruginosa in Brooklyn, NY: the preantibiotic era has returned.

Authors:  David Landman; John M Quale; David Mayorga; Adedeyo Adedeji; Kalyani Vangala; Jayshree Ravishankar; Carlos Flores; Steven Brooks
Journal:  Arch Intern Med       Date:  2002-07-08

10.  99mTc-Labeled UBI 29-41 peptide for monitoring the efficacy of antibacterial agents in mice infected with Staphylococcus aureus.

Authors:  Peter H Nibbering; Mick M Welling; Akke Paulusma-Annema; Carlo P J M Brouwer; Antonella Lupetti; Ernest K J Pauwels
Journal:  J Nucl Med       Date:  2004-02       Impact factor: 10.057
View more
  27 in total

Review 1.  New horizons for host defense peptides and lantibiotics.

Authors:  Michael John Dawson; Richard W Scott
Journal:  Curr Opin Pharmacol       Date:  2012-07-07       Impact factor: 5.547

2.  Activity of cecropin A-melittin hybrid peptides against colistin-resistant clinical strains of Acinetobacter baumannii: molecular basis for the differential mechanisms of action.

Authors:  José María Saugar; María Jesús Rodríguez-Hernández; Beatriz G de la Torre; María Eugenia Pachón-Ibañez; María Fernández-Reyes; David Andreu; Jerónimo Pachón; Luis Rivas
Journal:  Antimicrob Agents Chemother       Date:  2006-04       Impact factor: 5.191

3.  Synergistic activity of synthetic N-terminal peptide of human lactoferrin in combination with various antibiotics against carbapenem-resistant Klebsiella pneumoniae strains.

Authors:  P Morici; W Florio; C Rizzato; E Ghelardi; A Tavanti; G M Rossolini; A Lupetti
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2017-05-03       Impact factor: 3.267

Review 4.  Innate Immune Responses to Acinetobacter baumannii in the Airway.

Authors:  Sílvia Pires; Dane Parker
Journal:  J Interferon Cytokine Res       Date:  2019-04-23       Impact factor: 2.607

5.  Antimicrobial peptide hLF1-11 directs granulocyte-macrophage colony-stimulating factor-driven monocyte differentiation toward macrophages with enhanced recognition and clearance of pathogens.

Authors:  Anne M van der Does; Sylvia J P Bogaards; Bep Ravensbergen; Henry Beekhuizen; Jaap T van Dissel; Peter H Nibbering
Journal:  Antimicrob Agents Chemother       Date:  2009-11-23       Impact factor: 5.191

Review 6.  Acinetobacter baumannii: emergence of a successful pathogen.

Authors:  Anton Y Peleg; Harald Seifert; David L Paterson
Journal:  Clin Microbiol Rev       Date:  2008-07       Impact factor: 26.132

7.  Clinical outcomes of tigecycline alone or in combination with other antimicrobial agents for the treatment of patients with healthcare-associated multidrug-resistant Acinetobacter baumannii infections.

Authors:  Y-T Lee; S-M Tsao; P-R Hsueh
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2013-04-05       Impact factor: 3.267

8.  Killing of Mycobacterium avium by lactoferricin peptides: improved activity of arginine- and D-amino-acid-containing molecules.

Authors:  Tânia Silva; Bárbara Magalhães; Sílvia Maia; Paula Gomes; Kamran Nazmi; Jan G M Bolscher; Pedro N Rodrigues; Margarida Bastos; Maria Salomé Gomes
Journal:  Antimicrob Agents Chemother       Date:  2014-04-07       Impact factor: 5.191

9.  Analysis of Antimicrobial and Antibiofilm Activity of Human Milk Lactoferrin Compared to Bovine Lactoferrin against Multidrug Resistant and Susceptible Acinetobacter baumannii Clinical Isolates.

Authors:  Tyra M Avery; RaNashia L Boone; Jacky Lu; Sabrina K Spicer; Miriam A Guevara; Rebecca E Moore; Schuyler A Chambers; Shannon D Manning; Leon Dent; Dana Marshall; Steven M Damo; Steven D Townsend; Jennifer A Gaddy
Journal:  ACS Infect Dis       Date:  2021-06-09       Impact factor: 5.084

10.  Safety and tolerability of the antimicrobial peptide human lactoferrin 1-11 (hLF1-11).

Authors:  Walter J F M van der Velden; Thijs M P van Iersel; Nicole M A Blijlevens; J Peter Donnelly
Journal:  BMC Med       Date:  2009-09-08       Impact factor: 8.775
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.