Literature DB >> 15560698

Clinical abnormalities, intervention program, and school attendance of Down syndrome children in southern Thailand.

Somchit Jaruratanasirikul1, Somkiat Soponthammarak, Prasin Chanvitan, Pornprot Limprasert, Hutcha Sriplung, Wipawan Leelasamran, Seesuda Winothai.   

Abstract

BACKGROUND: Down syndrome is the most common chromosomal abnormality with an incidence of 1:700 livebirths. In southern Thailand, most Down syndrome patients are referred to Songklanagarind Hospital for surgical, medical treatment and/or stimulation intervention.
OBJECTIVE: To study the clinical features and school attendance of Down syndrome children. MATERIAL AND
METHOD: A total of 295 Down syndrome children attended Songklanagarind Hospital. The clinical features of Down syndrome, percentage of children receiving the stimulation intervention program, and attending school were studied.
RESULTS: Congenital heart disease was found in 38.6%, gastrointestinal anomalies 16.9%, hematologic malignancy 6.1%, and thyroid disorders 11.4%. The mortality rate of Down syndrome children was 13.2%. Most children (65.6%) received the early stimulation, but only 38.9% attended the speech intervention program within the first 2 years of life. Of the total 109 Down syndrome children aged over 5 years that are still being followed, only 74 (67.9%) attended school. The school attendance was correlated with the family income, but not correlated with the level of maternal or paternal education.
CONCLUSION: Congenital heart disease and gastrointestinal anomalies are commonly found in Down syndrome children. Most children received an early intervention program, but only 38.9% received speech intervention. In children aged >5 years, only 68% attended school, and school attendance was correlated with the family income.

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Year:  2004        PMID: 15560698

Source DB:  PubMed          Journal:  J Med Assoc Thai        ISSN: 0125-2208


  3 in total

1.  Study on the social adaptation of Chinese children with down syndrome.

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Journal:  Yonsei Med J       Date:  2007-06-30       Impact factor: 2.759

2.  Comorbidities in Down syndrome livebirths and health care intervention: an initial experience from the birth defects registry in Southern Thailand.

Authors:  Somchit Jaruratanasirikul; Wannee Limpitikul; Pathikan Dissaneevate; Paveena Booncharoen; Pongsak Tantichantakarun
Journal:  World J Pediatr       Date:  2017-01-15       Impact factor: 2.764

3.  An economic analysis of chromosome testing in couples with children who have structural chromosome abnormalities.

Authors:  Kittiphong Thiboonboon; Wantanee Kulpeng; Yot Teerawattananon
Journal:  PLoS One       Date:  2018-06-19       Impact factor: 3.240

  3 in total

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