| Literature DB >> 15558168 |
Márcia Cristina Ribeiro Andrade1, Carlos Torres Ribeiro, Virgílio Ferreira da Silva, Etelcia Moraes Molinaro, Miguel Angelo Brück Gonçalves, Marcos Antônio Pereira Marques, Pedro Hernan Cabello, José Paulo Gagliardi Leite.
Abstract
Physiological parameters of laboratory animals used for biomedical research is crucial for following several experimental procedures. With the intent to establish baseline biologic parameters for non-human primates held in closed colonies, hematological and morphometric data of captive monkeys were determined. Data of clinically healthy rhesus macaques (Macaca mulatta), cynomolgus monkeys (Macaca fascicularis), and squirrel monkeys (Saimiri sciureus) were collected over a period of five years. Animals were separated according to sex and divided into five age groups. Hematological data were compared with those in the literature by Student's t test. Discrepancies with significance levels of 0.1, 1 or 5% were found in the hematological studies. Growth curves showed that the sexual dimorphism of rhesus monkeys appeared at an age of four years. In earlier ages, the differences between sexes could not be distinguished (p < 0.05). Sexual dimorphism in both squirrel monkeys and cynomolgus monkeys occurred at an age of about 32 months. Data presented in this paper could be useful for comparative studies using primates under similar conditions.Entities:
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Year: 2004 PMID: 15558168 DOI: /S0074-02762004000600009
Source DB: PubMed Journal: Mem Inst Oswaldo Cruz ISSN: 0074-0276 Impact factor: 2.743