Literature DB >> 15556271

The Paris-Sud yeast structural genomics pilot-project: from structure to function.

Sophie Quevillon-Cheruel1, Dominique Liger, Nicolas Leulliot, Marc Graille, Anne Poupon, Inès Li de La Sierra-Gallay, Cong-Zhao Zhou, Bruno Collinet, Joël Janin, Herman Van Tilbeurgh.   

Abstract

We present here the outlines and results from our yeast structural genomics (YSG) pilot-project. A lab-scale platform for the systematic production and structure determination is presented. In order to validate this approach, 250 non-membrane proteins of unknown structure were targeted. Strategies and final statistics are evaluated. We finally discuss the opportunity of structural genomics programs to contribute to functional biochemical annotation.

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Year:  2004        PMID： 15556271     DOI： 10.1016/j.biochi.2004.09.013

Source DB:  PubMed          Journal:  Biochimie        ISSN： 0300-9084            Impact factor:   4.079


  5 in total

Review 1.  Structural genomics: the ultimate approach for rational drug design.

Authors:  Kenneth Lundstrom
Journal:  Mol Biotechnol       Date:  2006-10       Impact factor: 2.695

2.  Crystal structure of the yeast His6 enzyme suggests a reaction mechanism.

Authors:  Sophie Quevillon-Cheruel; Nicolas Leulliot; Marc Graille; Karine Blondeau; Joel Janin; Herman van Tilbeurgh
Journal:  Protein Sci       Date:  2006-06       Impact factor: 6.725

3.  Crystal structure of yeast YHR049W/FSH1, a member of the serine hydrolase family.

Authors:  Sophie Quevillon-Cheruel; Nicolas Leulliot; Marc Graille; Nadège Hervouet; Frank Coste; Hélène Bénédetti; Charles Zelwer; Joel Janin; Herman Van Tilbeurgh
Journal:  Protein Sci       Date:  2005-03-31       Impact factor: 6.725

4.  Crystal structure of yeast YER010Cp, a knotable member of the RraA protein family.

Authors:  Nicolas Leulliot; Sophie Quevillon-Cheruel; Marc Graille; Marc Schiltz; Karine Blondeau; Joël Janin; Herman Van Tilbeurgh
Journal:  Protein Sci       Date:  2005-10       Impact factor: 6.725

5.  Biochemical Characterization of a Novel α/β-Hydrolase/FSH from the White Shrimp Litopenaeus vannamei.

Authors:  Karina D Garcia-Orozco; Francisco Cinco-Moroyoqui; Lucía T Angulo-Sanchez; Enrique Marquez-Rios; Armando Burgos-Hernandez; Jose L Cardenas-Lopez; Carolina Gomez-Aguilar; David O Corona-Martinez; Gloria Saab-Rincon; Rogerio R Sotelo-Mundo
Journal:  Biomolecules       Date:  2019-10-31
  5 in total

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