Literature DB >> 15555542

Artemisinins: activities and actions.

Richard K Haynes1, Sanjeev Krishna.   

Abstract

Multidrug-resistant malaria caused by Plasmodium falciparum has severely limited treatment options over recent years. Artemisinins are still effective for treating uncomplicated as well as severe malaria, because resistance is not yet clinically apparent. This article reviews some clinically useful properties of artemisinins and how they might work.

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Year:  2004        PMID： 15555542     DOI： 10.1016/j.micinf.2004.09.002

Source DB:  PubMed          Journal:  Microbes Infect        ISSN： 1286-4579            Impact factor:   2.700


  28 in total

1.  In vitro assessment of methylene blue on chloroquine-sensitive and -resistant Plasmodium falciparum strains reveals synergistic action with artemisinins.

Authors:  Monique Akoachere; Kathrin Buchholz; Elisabeth Fischer; Jürgen Burhenne; Walter E Haefeli; R Heiner Schirmer; Katja Becker
Journal:  Antimicrob Agents Chemother       Date:  2005-11       Impact factor: 5.191

2.  Antimalarial action of artesunate involves DNA damage mediated by reactive oxygen species.

Authors:  Anusha M Gopalakrishnan; Nirbhay Kumar
Journal:  Antimicrob Agents Chemother       Date:  2014-10-27       Impact factor: 5.191

3.  Mechanism of antimalarial action of the synthetic trioxolane RBX11160 (OZ277).

Authors:  Anne-Catrin Uhlemann; Sergio Wittlin; Hugues Matile; Leyla Y Bustamante; Sanjeev Krishna
Journal:  Antimicrob Agents Chemother       Date:  2006-12-04       Impact factor: 5.191

4.  Investigations into the role of the Plasmodium falciparum SERCA (PfATP6) L263E mutation in artemisinin action and resistance.

Authors:  Stephanie Gaw Valderramos; Daniel Scanfeld; Anne-Catrin Uhlemann; David A Fidock; Sanjeev Krishna
Journal:  Antimicrob Agents Chemother       Date:  2010-06-21       Impact factor: 5.191

5.  The binding modes and binding affinities of artemisinin derivatives with Plasmodium falciparum Ca2+-ATPase (PfATP6).

Authors:  Pradeep Kumar Naik; Mani Srivastava; Prasad Bajaj; Sankalp Jain; Abhishek Dubey; Piyush Ranjan; Rishay Kumar; Harvinder Singh
Journal:  J Mol Model       Date:  2010-05-12       Impact factor: 1.810

6.  Artemisinin induces calcium-dependent protein secretion in the protozoan parasite Toxoplasma gondii.

Authors:  Kisaburo Nagamune; Wandy L Beatty; L David Sibley
Journal:  Eukaryot Cell       Date:  2007-08-31

7.  Artemisinin resistance in Plasmodium falciparum: A process linked to dormancy?

Authors:  Qin Cheng; Dennis E Kyle; Michelle L Gatton
Journal:  Int J Parasitol Drugs Drug Resist       Date:  2012-01-27       Impact factor: 4.077

8.  Artemisone and artemiside control acute and reactivated toxoplasmosis in a murine model.

Authors:  Ildiko R Dunay; Wing Chi Chan; Richard K Haynes; L David Sibley
Journal:  Antimicrob Agents Chemother       Date:  2009-07-27       Impact factor: 5.191

9.  A study on antimalarial artemisinin derivatives using MEP maps and multivariate QSAR.

Authors:  Fábio José B Cardoso; Antonio Florêncio de Figueiredo; Maycon da Silva Lobato; Ricardo Moraes de Miranda; Ruth Catarine O de Almeida; José Ciríaco Pinheiro
Journal:  J Mol Model       Date:  2007-10-30       Impact factor: 1.810

10.  Artemisinin-resistant mutants of Toxoplasma gondii have altered calcium homeostasis.

Authors:  Kisaburo Nagamune; Silvia N J Moreno; L David Sibley
Journal:  Antimicrob Agents Chemother       Date:  2007-08-13       Impact factor: 5.191
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