Literature DB >> 1555494

Acyl glucuronides revisited: is the glucuronidation process a toxification as well as a detoxification mechanism?

H Spahn-Langguth1, L Z Benet.   

Abstract

Entities:  

Mesh：

Substances：

Year:  1992        PMID： 1555494     DOI： 10.3109/03602539208996289

Source DB:  PubMed          Journal:  Drug Metab Rev        ISSN： 0360-2532            Impact factor:   4.518


× No keyword cloud information.
  41 in total

1.  Sex hormones differentially regulate isoforms of UDP-glucuronosyltransferase.

Authors:  S I Strasser; S A Smid; M L Mashford; P V Desmond
Journal:  Pharm Res       Date:  1997-09       Impact factor: 4.200

2.  Glucuronidation of drugs and drug-induced toxicity in humanized UDP-glucuronosyltransferase 1 mice.

Authors:  Yuki Kutsuno; Tomoo Itoh; Robert H Tukey; Ryoichi Fujiwara
Journal:  Drug Metab Dispos       Date:  2014-04-24       Impact factor: 3.922

3.  Reaction of acyl glucuronides with insulin in vitro: identification of an imine mechanism by electrospray ionization mass spectrometry.

Authors:  J H Liu; C D Marquez; S T Weintraub; P C Smith
Journal:  Pharm Res       Date:  1998-02       Impact factor: 4.200

Review 4.  Chirality and nonsteroidal anti-inflammatory drugs.

Authors:  P J Hayball
Journal:  Drugs       Date:  1996       Impact factor: 9.546

5.  CPY3A4-mediated α-hydroxyaldehyde formation in saquinavir metabolism.

Authors:  Feng Li; Jie Lu; Xiaochao Ma
Journal:  Drug Metab Dispos       Date:  2013-11-08       Impact factor: 3.922

6.  Evidence for covalent binding of acyl glucuronides to serum albumin via an imine mechanism as revealed by tandem mass spectrometry.

Authors:  A Ding; J C Ojingwa; A F McDonagh; A L Burlingame; L Z Benet
Journal:  Proc Natl Acad Sci U S A       Date:  1993-05-01       Impact factor: 11.205

7.  Acylglucuronide in alkaline conditions: migration vs. hydrolysis.

Authors:  Florent Di Meo; Michele Steel; Picard Nicolas; Pierre Marquet; Jean-Luc Duroux; Patrick Trouillas
Journal:  J Mol Model       Date:  2013-02-19       Impact factor: 1.810

8.  Stereoselective flunoxaprofen-S-acyl-glutathione thioester formation mediated by acyl-CoA formation in rat hepatocytes.

Authors:  Mark P Grillo; Jill C M Wait; Michelle Tadano Lohr; Smriti Khera; Leslie Z Benet
Journal:  Drug Metab Dispos       Date:  2010-01       Impact factor: 3.922

9.  Studies on the renal excretion of the acyl glucuronide, phenolic glucuronide and sulphate conjugates of diflunisal.

Authors:  R G Dickinson; A R King; G E McKinnon; W D Hooper; M J Eadie; G K Herkes
Journal:  Br J Clin Pharmacol       Date:  1993-06       Impact factor: 4.335

10.  Relative importance of intestinal and hepatic glucuronidation-impact on the prediction of drug clearance.

Authors:  Helen E Cubitt; J Brian Houston; Aleksandra Galetin
Journal:  Pharm Res       Date:  2009-01-31       Impact factor: 4.200
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.