| Literature DB >> 15554252 |
Chung-Kyu Ryu1, Ju-Yeon Shim, You-Jin Yi, Ik Hwa Choi, Mi Jin Chae, Ja-Young Han, Ok-Jai Jung.
Abstract
5,8-Quinazolinediones modified at positions 6 and 7 were synthesized and tested for in vitro antifungal activities against Candida species and Aspergillus niger. Most of 5,8-quinazolinediones 3-5 generally exhibited potent antifungal activity. 6-Arylamino-7-chloro-5,8-quinazolinediones (3) generally showed more potent antifungal activity than 7-arylthio-5,8-quinzolinediones (4) and 6,7-bis-(arylthio)-5,8-quinazolinediones (5).Entities:
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Year: 2004 PMID： 15554252 DOI： 10.1007/bf02975419
Source DB: PubMed Journal: Arch Pharm Res ISSN： 0253-6269 Impact factor: 4.946