| Literature DB >> 15550951 |
Abstract
Drug addiction manifests as a compulsive drive to take a drug despite serious adverse consequences. This aberrant behaviour has traditionally been viewed as bad "choices" that are made voluntarily by the addict. However, recent studies have shown that repeated drug use leads to long-lasting changes in the brain that undermine voluntary control. This, combined with new knowledge of how environmental, genetic and developmental factors contribute to addiction, should bring about changes in our approach to the prevention and treatment of addiction.Entities:
Mesh:
Year: 2004 PMID: 15550951 DOI: 10.1038/nrn1539
Source DB: PubMed Journal: Nat Rev Neurosci ISSN: 1471-003X Impact factor: 34.870