| Literature DB >> 15549414 |
Z A Massy1, C Mazière, S Kamel, M Brazier, G Choukroun, C Tribouilloy, M Slama, M Andrejak, J C Mazière.
Abstract
Vascular and/or valvular calcifications in patients with chronic kidney disease (CKD) appear to indicate a poor prognosis in terms of overall survival and cardiovascular morbidity and mortality. Inflammation and oxidative stress represent new features of the arterial and/or valvular calcification process. However, only limited observational and epidemiological data are available in these areas. Therefore, the link between inflammation, oxidation and vascular and/or valvular calcifications deserves careful consideration in CKD patients, since they may become targets for the development of new therapeutic strategies.Entities:
Mesh:
Year: 2004 PMID: 15549414 DOI: 10.1007/s00467-004-1623-9
Source DB: PubMed Journal: Pediatr Nephrol ISSN: 0931-041X Impact factor: 3.714