| Literature DB >> 15548070 |
Kateri A Ahrendt1, Robert M Williams.
Abstract
The ADE fragment of nakadomarin A has been synthesized in nine linear steps from commercial material. The key transformation is an asymmetric azomethine ylide [1,3]-dipolar cycloaddition to establish the AD-spirocyclic system containing three of the four stereocenters of the natural product. [reaction: see text]Entities:
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Year: 2004 PMID： 15548070 DOI： 10.1021/ol048126e
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005