Literature DB >> 15546855

Surprising versatility of Na+-glucose cotransporters: SLC5.

Ernest M Wright1, Donald D F Loo, Bruce A Hirayama, Eric Turk.   

Abstract

SLC5 is an ancient gene family with 11 members in the human genome. These membrane proteins have diverse, multiple functions ranging from actively transporting solutes, ions, and water, to channeling water and urea, to sensing glucose in cholinergic neurons. Metabolic disorders have been identified that are associated with congenital mutations in two of the human genes.

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Year:  2004        PMID： 15546855     DOI： 10.1152/physiol.00026.2004

Source DB:  PubMed          Journal:  Physiology (Bethesda)        ISSN： 1548-9221


  47 in total

1.  Water permeation through the sodium-dependent galactose cotransporter vSGLT.

Authors:  Seungho Choe; John M Rosenberg; Jeff Abramson; Ernest M Wright; Michael Grabe
Journal:  Biophys J       Date:  2010-10-06       Impact factor: 4.033

2.  A fluorescence method for measurement of glucose transport in kidney cells.

Authors:  Amy B Blodgett; Rajendra K Kothinti; Ivan Kamyshko; David H Petering; Suresh Kumar; Niloofar M Tabatabai
Journal:  Diabetes Technol Ther       Date:  2011-04-21       Impact factor: 6.118

3.  Functional role of sodium glucose transporter in high glucose-mediated angiotensin type 1 receptor downregulation in human proximal tubule cells.

Authors:  Rekha Yesudas; Russell Snyder; Thomas Abbruscato; Thomas Thekkumkara
Journal:  Am J Physiol Renal Physiol       Date:  2012-05-30

4.  Present and Prospective Pharmacotherapy for the Management of Patients with Type 2 Diabetes.

Authors:  Leonor Corsino; Mary Elizabeth Cox; Jennifer Rowel; Jennifer B Green
Journal:  Clin Med Ther       Date:  2009-08-27

5.  Salty dog, an SLC5 symporter, modulates Drosophila response to salt stress.

Authors:  Konstantinos Stergiopoulos; Pablo Cabrero; Shireen-Anne Davies; Julian A T Dow
Journal:  Physiol Genomics       Date:  2008-11-18       Impact factor: 3.107

6.  A prospective analysis of co-processed non-ionic surfactants in enhancing permeability of a model hydrophilic drug.

Authors:  Mohammed M Alvi; Parnali Chatterjee
Journal:  AAPS PharmSciTech       Date:  2013-12-20       Impact factor: 3.246

7.  The sodium/galactose symporter crystal structure is a dynamic, not so occluded state.

Authors:  Elia Zomot; Ivet Bahar
Journal:  Mol Biosyst       Date:  2010-03-31

8.  Molecular mechanism of vSGLT inhibition by gneyulin reveals antiseptic properties against multidrug-resistant gram-negative bacteria.

Authors:  Daniel Wiczew; Anna Borowska; Kinga Szkaradek; Tomasz Biegus; Kamil Wozniak; Marcelina Pyclik; Magdalena Sitarska; Lukasz Jaszewski; Lukasz Radosinski; Beata Hanus-Lorenz; Sebastian Kraszewski
Journal:  J Mol Model       Date:  2019-06-11       Impact factor: 1.810

9.  Na+-glucose cotransporter SGLT1 protein in salivary glands: potential involvement in the diabetes-induced decrease in salivary flow.

Authors:  R Sabino-Silva; H S Freitas; M L Lamers; M M Okamoto; M F Santos; U F Machado
Journal:  J Membr Biol       Date:  2009-02-24       Impact factor: 1.843

10.  Cloning and functional identification of slc5a12 as a sodium-coupled low-affinity transporter for monocarboxylates (SMCT2).

Authors:  Sonne R Srinivas; Elangovan Gopal; Lina Zhuang; Shirou Itagaki; Pamela M Martin; You-Jun Fei; Vadivel Ganapathy; Puttur D Prasad
Journal:  Biochem J       Date:  2005-12-15       Impact factor: 3.857
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