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Literature DB >> 15546854

Regulation of ion transport by the NHERF family of PDZ proteins.

Shirish Shenolikar¹, James W Voltz, Rochelle Cunningham, Edward J Weinman.

Abstract

NHERFs are the best-studied apical PDZ proteins that are highly expressed in epithelial cells. Molecular and cellular studies over the past decade show that NHERFs regulate the targeting or trafficking of ion transporters and other membrane proteins and transduce physiological and pathophysiological signals that regulate ion homeostasis in mammals.

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Year: 2004 PMID： 15546854 DOI： 10.1152/physiol.00020.2004

Source DB: PubMed Journal: Physiology (Bethesda) ISSN： 1548-9221

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Cited

64 in total

1. Apical scaffolding protein NHERF2 modulates the localization of alternatively spliced plasma membrane Ca2+ pump 2B variants in polarized epithelial cells.

Authors: Rita Padányi; Yuning Xiong; Géza Antalffy; Krisztina Lór; Katalin Pászty; Emanuel E Strehler; Agnes Enyedi
Journal: J Biol Chem Date: 2010-07-27 Impact factor: 5.157

2. Activation of nanoscale allosteric protein domain motion revealed by neutron spin echo spectroscopy.

Authors: Bela Farago; Jianquan Li; Gabriel Cornilescu; David J E Callaway; Zimei Bu
Journal: Biophys J Date: 2010-11-17 Impact factor: 4.033

3. Alterations in the proteome of the NHERF2 knockout mouse jejunal brush border membrane vesicles.

Authors: M Donowitz; S Singh; P Singh; M Chakraborty; Y Chen; R Murtazina; M Gucek; R N Cole; N C Zachos; F F Salahuddin; O Kovbasnjuk; N Broere; W G Smalley-Freed; A B Reynolds; A L Hubbard; U Seidler; E Weinman; H R de Jonge; B M Hogema; X Li
Journal: Physiol Genomics Date: 2011-03-22 Impact factor: 3.107

4. Postnatal developmental expression of the PDZ scaffolds Na+ -H+ exchanger regulatory factors 1 and 2 in the rat cochlea.

Authors: Refik Kanjhan; Deanne H Hryciw; C Chris Yun; Mark C Bellingham; Philip Poronnik
Journal: Cell Tissue Res Date: 2005-09-14 Impact factor: 5.249

5. Hair bundles are specialized for ATP delivery via creatine kinase.

Authors: Jung-Bum Shin; Femke Streijger; Andy Beynon; Theo Peters; Laura Gadzala; Debra McMillen; Cory Bystrom; Catharina E E M Van der Zee; Theo Wallimann; Peter G Gillespie
Journal: Neuron Date: 2007-02-01 Impact factor: 17.173

6. Astrocytic and neuronal localization of the scaffold protein Na+/H+ exchanger regulatory factor 2 (NHERF-2) in mouse brain.

Authors: Maryse Paquet; Masaaki Kuwajima; C Chris Yun; Yoland Smith; Randy A Hall
Journal: J Comp Neurol Date: 2006-02-10 Impact factor: 3.215

Regulation of ion transport by the NHERF family of PDZ proteins.

1. Apical scaffolding protein NHERF2 modulates the localization of alternatively spliced plasma membrane Ca2+ pump 2B variants in polarized epithelial cells.

2. Activation of nanoscale allosteric protein domain motion revealed by neutron spin echo spectroscopy.

3. Alterations in the proteome of the NHERF2 knockout mouse jejunal brush border membrane vesicles.

4. Postnatal developmental expression of the PDZ scaffolds Na+ -H+ exchanger regulatory factors 1 and 2 in the rat cochlea.

5. Hair bundles are specialized for ATP delivery via creatine kinase.

6. Astrocytic and neuronal localization of the scaffold protein Na+/H+ exchanger regulatory factor 2 (NHERF-2) in mouse brain.

7. Kidney kinase network regulates renal ion cotransport.

Review 8. NHERF and regulation of the renal sodium-hydrogen exchanger NHE3.

9. Ligand-induced dynamic changes in extended PDZ domains from NHERF1.

10. NHERF1 regulates parathyroid hormone receptor desensitization: interference with beta-arrestin binding.