| Literature DB >> 15546716 |
Patrizia Calí1, Lars Naerum, Seema Mukhija, Anders Hjelmencrantz.
Abstract
A series of isoxazole-3-hydroxamic acid derivatives has been identified as a new class of small, nonpeptidic inhibitors of peptide deformylase (PDF). The synthesis, enzyme inhibition and preliminary investigation of the binding mode of this potential antibacterial compounds are reported.Entities:
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Year: 2004 PMID： 15546716 DOI： 10.1016/j.bmcl.2004.09.087
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823