| Literature DB >> 15546714 |
Shawn P Maddaford1, Mina Motamed, Kevin B Turner, Min Soo K Choi, Jailall Ramnauth, Suman Rakhit, Robert R Hudgins, Daniele Fabris, Philip E Johnson.
Abstract
We report the identification of a novel compound that binds to the Escherichia coli 16S ribosomal A-site. Binding by the compound was observed using nuclear magnetic resonance and mass spectrometry techniques. We show that the compound binds in the same position in the A-site RNA as occupied by the aminoglycoside class of antibiotics.Entities:
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Year: 2004 PMID： 15546714 DOI： 10.1016/j.bmcl.2004.09.088
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823