Literature DB >> 15546611

B cell development leads off with a base hit: dU:dG mismatches in class switching and hypermutation.

Gregory S Lee1, Vicky L Brandt, David B Roth.   

Abstract

The mechanisms underlying somatic hypermutation (SHM) and class switch recombination (CSR) have been the subject of much debate. Recent studies from the Neuberger and Honjo labs have lent insight into these distinct processes, and we discuss a new, comprehensive model for how AID, uracil DNA glycosylase (UNG) and the mismatch repair system function in both SHM and CSR.

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Year:  2004        PMID： 15546611     DOI： 10.1016/j.molcel.2004.11.008

Source DB:  PubMed          Journal:  Mol Cell        ISSN： 1097-2765            Impact factor:   17.970


  8 in total

1.  IL-23 Promotes a Coordinated B Cell Germinal Center Program for Class-Switch Recombination to IgG2b in BXD2 Mice.

Authors:  Huixian Hong; Min Gao; Qi Wu; PingAr Yang; Shanrun Liu; Hao Li; Peter D Burrows; Daniel Cua; Jake Y Chen; Hui-Chen Hsu; John D Mountz
Journal:  J Immunol       Date:  2020-06-17       Impact factor: 5.422

2.  DNA polymerase theta contributes to the generation of C/G mutations during somatic hypermutation of Ig genes.

Authors:  Keiji Masuda; Rika Ouchida; Arata Takeuchi; Takashi Saito; Haruhiko Koseki; Kiyoko Kawamura; Masatoshi Tagawa; Takeshi Tokuhisa; Takachika Azuma; Jiyang O-Wang
Journal:  Proc Natl Acad Sci U S A       Date:  2005-09-19       Impact factor: 11.205

3.  Physical and functional interaction of human nuclear uracil-DNA glycosylase with proliferating cell nuclear antigen.

Authors:  Rinkei Ko; Samuel E Bennett
Journal:  DNA Repair (Amst)       Date:  2005-10-07

4.  It takes two: communication between homologous alleles preserves genomic stability during V(D)J recombination.

Authors:  Vicky L Brandt; Susannah L Hewitt; Jane A Skok
Journal:  Nucleus       Date:  2010 Jan-Feb       Impact factor: 4.197

Review 5.  The ageing human B cell repertoire: a failure of selection?

Authors:  D K Dunn-Walters
Journal:  Clin Exp Immunol       Date:  2015-10-06       Impact factor: 4.330

6.  Lack of MSH2 involvement differentiates V(D)J recombination from other non-homologous end joining events.

Authors:  Mani Larijani; Ahmad Zaheen; Darina Frieder; Yuxun Wang; Gillian E Wu; Winfried Edelmann; Alberto Martin
Journal:  Nucleic Acids Res       Date:  2005-11-27       Impact factor: 16.971

Review 7.  AID to overcome the limitations of genomic information by introducing somatic DNA alterations.

Authors:  Tasuku Honjo; Masamichi Muramatsu; Hitoshi Nagaoka; Kazuo Kinoshita; Reiko Shinkura
Journal:  Proc Jpn Acad Ser B Phys Biol Sci       Date:  2006-05       Impact factor: 3.493

Review 8.  Coronavirus disease 2019 (COVID-19), human erythrocytes and the PKC-alpha/-beta inhibitor chelerythrine -possible therapeutic implication.

Authors:  Mehrdad Ghashghaeinia; Peter Dreischer; Thomas Wieder; Martin Köberle
Journal:  Cell Cycle       Date:  2020-12-11       Impact factor: 4.534
  8 in total

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