Literature DB >> 15544261

Palpation imaging using a haptic system for virtual reality applications in medicine.

W Khaled1, S Reichling, O T Bruhns, H Boese, M Baumann, G Monkman, S Egersdoerfer, D Klein, A Tunayar, H Freimuth, A Lorenz, A Pessavento, H Ermert.   

Abstract

In the field of medical diagnosis, there is a strong need to determine mechanical properties of biological tissue, which are of histological and pathological relevance. Malignant tumors are significantly stiffer than surrounding healthy tissue. One of the established diagnosis procedures is the palpation of body organs and tissue. Palpation is used to measure swelling, detect bone fracture, find and measure pulse, or to locate changes in the pathological state of tissue and organs. Current medical practice routinely uses sophisticated diagnostic tests through magnetic resonance imaging (MRI), computed tomography (CT) and ultrasound (US) imaging. However, they cannot provide direct measure of tissue elasticity. Last year we presented the concept of the first haptic sensor actuator system to visualize and reconstruct mechanical properties of tissue using ultrasonic elastography and a haptic display with electrorheological fluids. We developed a real time strain imaging system for tumor diagnosis. It allows biopsies simultaneously to conventional ultrasound B-Mode and strain imaging investigations. We deduce the relative mechanical properties by using finite element simulations and numerical solution models solving the inverse problem. Various modifications on the haptic sensor actuator system have been investigated. This haptic system has the potential of inducing real time substantial forces, using a compact lightweight mechanism which can be applied to numerous areas including intraoperative navigation, telemedicine, teaching and telecommunication.

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Year:  2004        PMID: 15544261     DOI: 10.1142/9789812702678_0055

Source DB:  PubMed          Journal:  Stud Health Technol Inform        ISSN: 0926-9630


  5 in total

Review 1.  Modelling the Tumor Microenvironment: Recapitulating Nano- and Micro-Scale Properties that Regulate Tumor Progression.

Authors:  Danielle Vahala; Yu Suk Choi
Journal:  Front Cell Dev Biol       Date:  2022-06-14

Review 2.  Three-dimensional context regulation of metastasis.

Authors:  Janine T Erler; Valerie M Weaver
Journal:  Clin Exp Metastasis       Date:  2008-09-24       Impact factor: 5.150

Review 3.  Mechanics, malignancy, and metastasis: the force journey of a tumor cell.

Authors:  Sanjay Kumar; Valerie M Weaver
Journal:  Cancer Metastasis Rev       Date:  2009-06       Impact factor: 9.264

4.  Mechanical stress downregulates MHC class I expression on human cancer cell membrane.

Authors:  Rosanna La Rocca; Rossana Tallerico; Almosawy Talib Hassan; Gobind Das; Tadepally Lakshmikanth; Lakshmikanth Tadepally; Marco Matteucci; Carlo Liberale; Maria Mesuraca; Domenica Scumaci; Francesco Gentile; Gheorghe Cojoc; Gerardo Perozziello; Antonio Ammendolia; Adriana Gallo; Klas Kärre; Giovanni Cuda; Patrizio Candeloro; Enzo Di Fabrizio; Ennio Carbone
Journal:  PLoS One       Date:  2014-12-26       Impact factor: 3.240

5.  Evaluation of stiffness feedback for hard nodule identification on a phantom silicone model.

Authors:  Min Li; Jelizaveta Konstantinova; Guanghua Xu; Bo He; Vahid Aminzadeh; Jun Xie; Helge Wurdemann; Kaspar Althoefer
Journal:  PLoS One       Date:  2017-03-01       Impact factor: 3.240

  5 in total

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