Literature DB >> 15543275

Biomimetic synthesis of the pyrrolobenzoxazine core of paeciloxazine.

Dirk Schwaebisch1, Kirill Tchabanenko, Robert M Adlington, Andrew M Cowley, Jack E Baldwin.   

Abstract

Starting from a protected L-tryptophan derivative the pyrrolobenzoxazine core unit of paeciloxazine can be synthesized in two oxidation steps.

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Year:  2004        PMID： 15543275     DOI： 10.1039/b412300j

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  4 in total

1.  Synthesis and preliminary biological studies of 3-substituted indoles accessed by a palladium-catalyzed enantioselective alkene difunctionalization reaction.

Authors:  Tejas P Pathak; Keith M Gligorich; Bryan E Welm; Matthew S Sigman
Journal:  J Am Chem Soc       Date:  2010-06-16       Impact factor: 15.419

2.  Straightforward Access to Hexahydropyrrolo[2,3-b]indole Core by a Regioselective C3-Azo Coupling Reaction of Arenediazonium Compounds with Tryptamines.

Authors:  David E Stephens; Oleg V Larionov
Journal:  European J Org Chem       Date:  2014-06-01

3.  Biosynthesis of Terpenoid-Pyrrolobenzoxazine Hybrid Natural Product CJ-12662.

Authors:  Wei Cheng; Mengbin Chen; Masao Ohashi; Yi Tang
Journal:  Angew Chem Int Ed Engl       Date:  2022-02-03       Impact factor: 16.823

4.  The second enzyme in pyrrolnitrin biosynthetic pathway is related to the heme-dependent dioxygenase superfamily.

Authors:  Walter De Laurentis; Leang Khim; J L Ross Anderson; Ariane Adam; Kenneth A Johnson; Robert S Phillips; Stephen K Chapman; Karl-Heinz van Pee; James H Naismith
Journal:  Biochemistry       Date:  2007-10-09       Impact factor: 3.162
  4 in total

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