| Literature DB >> 15542900 |
Kimberly Walter1, James Eshleman, Michael Goggins.
Abstract
Xenotransplantation (xenografting) of primary cancers or cancer cell lines into immunodeficient mice is a commonly used technique to assess tumor growth in response to a variety of experimental agents. When primary pancreatic cancers are xenografted, cancer cells proliferate in the mouse, but the human stroma does not. This growth pattern enables facile genetic analysis of cancer genetics profiles without the contamination of admixed stromal cells typical of primary cancers.Entities:
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Year: 2005 PMID： 15542900 DOI： 10.1385/1-59259-780-7:103
Source DB: PubMed Journal: Methods Mol Med ISSN： 1543-1894