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Literature DB >> 15542693

RNA degradation induced by the herpes simplex virus vhs protein proceeds 5' to 3' in vitro.

Jorge Perez-Parada¹, Holly A Saffran, James R Smiley.

Abstract

The herpes simplex virus virion host shutoff protein (vhs) is an mRNA-specific RNase that contributes to shutoff of host protein synthesis. We show here that vhs-induced mRNA decay proceeds 5' to 3' in an in vitro assay system derived from rabbit reticulocyte lysate.

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Year: 2004 PMID： 15542693 PMCID： PMC525032 DOI： 10.1128/JVI.78.23.13391-13394.2004

Source DB: PubMed Journal: J Virol ISSN： 0022-538X Impact factor: 5.103

21 in total

1. Picornavirus internal ribosome entry site elements target RNA cleavage events induced by the herpes simplex virus virion host shutoff protein.

Authors: M M Elgadi; J R Smiley
Journal: J Virol Date: 1999-11 Impact factor: 5.103

2. Herpes simplex virus vhs protein.

Authors: J R Smiley; M M Elgadi; H A Saffran
Journal: Methods Enzymol Date: 2001 Impact factor: 1.600

3. mRNA degradation by the virion host shutoff (Vhs) protein of herpes simplex virus: genetic and biochemical evidence that Vhs is a nuclease.

Authors: David N Everly; Pinghui Feng; I Saira Mian; G Sullivan Read
Journal: J Virol Date: 2002-09 Impact factor: 5.103

Review 4. Herpes simplex virus virion host shutoff protein: immune evasion mediated by a viral RNase?

Authors: James R Smiley
Journal: J Virol Date: 2004-02 Impact factor: 5.103

5. The vhs1 mutant form of herpes simplex virus virion host shutoff protein retains significant internal ribosome entry site-directed RNA cleavage activity.

Authors: P Lu; H A Saffran; J R Smiley
Journal: J Virol Date: 2001-01 Impact factor: 5.103

6. The role of the UL41 gene of herpes simplex virus type 1 in evasion of non-specific host defence mechanisms during primary infection.

Authors: T Suzutani; M Nagamine; T Shibaki; M Ogasawara; I Yoshida; T Daikoku; Y Nishiyama; M Azuma
Journal: J Gen Virol Date: 2000-07 Impact factor: 3.891

7. mRNA decay during herpesvirus infections: interaction between a putative viral nuclease and a cellular translation factor.

Authors: P Feng; D N Everly; G S Read
Journal: J Virol Date: 2001-11 Impact factor: 5.103

8. Pathogenesis of herpes simplex virus type 2 virion host shutoff (vhs) mutants.

Authors: Tracy J Smith; Lynda A Morrison; David A Leib
Journal: J Virol Date: 2002-03 Impact factor: 5.103

9. Herpes simplex virus type 2 virion host shutoff protein regulates alpha/beta interferon but not adaptive immune responses during primary infection in vivo.

Authors: Jenny A Murphy; Rebecca J Duerst; Tracy J Smith; Lynda A Morrison
Journal: J Virol Date: 2003-09 Impact factor: 5.103

10. The stress-inducible immediate-early responsive gene IEX-1 is activated in cells infected with herpes simplex virus 1, but several viral mechanisms, including 3' degradation of its RNA, preclude expression of the gene.

Authors: Brunella Taddeo; Audrey Esclatine; Weiran Zhang; Bernard Roizman
Journal: J Virol Date: 2003-06 Impact factor: 5.103

11 in total

1. Evidence for translational regulation by the herpes simplex virus virion host shutoff protein.

Authors: Holly A Saffran; G Sullivan Read; James R Smiley
Journal: J Virol Date: 2010-03-31 Impact factor: 5.103

2. Herpes simplex virus ICP27 is required for virus-induced stabilization of the ARE-containing IEX-1 mRNA encoded by the human IER3 gene.

Authors: Jennifer A Corcoran; Wei-Li Hsu; James R Smiley
Journal: J Virol Date: 2006-10 Impact factor: 5.103

3. The herpes simplex virus type 1 vhs-UL41 gene secures viral replication by temporarily evading apoptotic cellular response to infection: Vhs-UL41 activity might require interactions with elements of cellular mRNA degradation machinery.

Authors: Ari Barzilai; Ifaat Zivony-Elbom; Ronit Sarid; Eran Noah; Niza Frenkel
Journal: J Virol Date: 2006-01 Impact factor: 5.103

4. The U(L)41 protein of herpes simplex virus 1 degrades RNA by endonucleolytic cleavage in absence of other cellular or viral proteins.

Authors: Brunella Taddeo; Weiran Zhang; Bernard Roizman
Journal: Proc Natl Acad Sci U S A Date: 2006-02-13 Impact factor: 11.205

5. Selective degradation of mRNAs by the HSV host shutoff RNase is regulated by the UL47 tegument protein.

Authors: Minfeng Shu; Brunella Taddeo; Weiran Zhang; Bernard Roizman
Journal: Proc Natl Acad Sci U S A Date: 2013-04-15 Impact factor: 11.205

6. Herpes simplex virus infection stabilizes cellular IEX-1 mRNA.

Authors: Wei-Li Hsu; Holly A Saffran; James R Smiley
Journal: J Virol Date: 2005-04 Impact factor: 5.103

7. Tristetraprolin Recruits the Herpes Simplex Virion Host Shutoff RNase to AU-Rich Elements in Stress Response mRNAs To Enable Their Cleavage.

Authors: Minfeng Shu; Brunella Taddeo; Bernard Roizman
Journal: J Virol Date: 2015-03-11 Impact factor: 5.103

8. Comparison of immunogenicity and protective efficacy of genital herpes vaccine candidates herpes simplex virus 2 dl5-29 and dl5-29-41L in mice and guinea pigs.

Authors: Yo Hoshino; Lesley Pesnicak; Kennichi C Dowdell; Juan Lacayo; Timothy Dudek; David M Knipe; Stephen E Straus; Jeffrey I Cohen
Journal: Vaccine Date: 2008-06-02 Impact factor: 3.641

9. mRNA decay during herpes simplex virus (HSV) infections: mutations that affect translation of an mRNA influence the sites at which it is cleaved by the HSV virion host shutoff (Vhs) protein.

Authors: Lora A Shiflett; G Sullivan Read
Journal: J Virol Date: 2012-10-17 Impact factor: 5.103

10. Small interfering RNAs that deplete the cellular translation factor eIF4H impede mRNA degradation by the virion host shutoff protein of herpes simplex virus.

Authors: Nandini Sarma; Deepali Agarwal; Lora A Shiflett; G Sullivan Read
Journal: J Virol Date: 2008-04-30 Impact factor: 5.103